Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin.

AIM

The purpose of this study was to assess the push-out bond strength of mineral trioxide aggregate (MTA) to dentin after the use of intracanal medicaments, including calcium hydroxide [Ca(OH)], calcium hydroxide with chlorhexidine [CHX], double antibiotic paste [DAP], and modified triple antibiotic paste [mTAP], for 3 and 6 weeks and identify the failure modes related to each medicament.

MATERIALS AND METHODS

Eighty extracted mandibular premolars were decoronated and instrumented to size 30 (Protaper Universal F3). Peeso reamers #1-#6, followed by 2.5% NaOCl, 17% EDTA, and distilled water for irrigation, were applied in sequence. The specimens were divided into four groups with n = 20/group: Group 1, Ca(OH); Group 2, Ca(OH) + CHX; Group 3, DAP; and Group 4, mTAP. The medicaments were deposited using a Lentulo spiral, and the samples were kept in saline at both 3 and 6 weeks.

RESULTS

MTA dislocation resistance significantly decreased with time, i.e., between 3 weeks and 6 weeks ( < 0.05). There was no significant difference at 3 weeks between Ca(OH) and Ca(OH) + CHX ( = 0.791) or at 6 weeks between Ca(OH) and mTAP ( = 1.000). Calcium hydroxide provided the highest bonding strength, while DAP had the lowest at both time points.

CONCLUSION

The highest bond strength was shown by calcium hydroxide at both 3 and 6 weeks, while the lowest bond strength was obtained with DAP.