• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

小儿葡萄球菌烫伤样皮肤综合征合并耐甲氧西林金黄色葡萄球菌感染及类固醇滥用:一例报告

Pediatric Staphylococcal Scalded Skin Syndrome Complicated by Methicillin-Resistant Staphylococcus Aureus and Steroid Abuse: A Case Report.

作者信息

Jha Ujjwal Kumar, Yadav Ajay Kumar

机构信息

Grande International Hospital, Dhapasi, Kathmandu, Nepal.

Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2024 Oct;62(278):697-699. doi: 10.31729/jnma.8770. Epub 2024 Oct 31.

DOI:10.31729/jnma.8770
PMID:40655879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11619542/
Abstract

Staphylococcal Scalded Skin Syndrome (SSSS) is a severe exfoliative skin condition primarily affecting children, caused by the toxins produced by This case report describes the clinical presentation, diagnostic challenges, and successful management of SSSS complicated by Methicillin-Resistant (MRSA) in a pediatric patient. A pediatric patient presented with a two-week history of pruritic vesiculobullous eruptions that progressively worsened. Despite initial treatments with various topical and oral medications including steroid and antibiotic ointments, the lesions continued to progress. A wound culture identified heavy growth of MRSA, prompting a change in the treatment regimen, resulting in significant clinical improvement. This case underscores the importance of accurate diagnosis and timely intervention in the management of SSSS, particularly when complicated by MRSA. The successful outcome with appropriate antibiotic therapy highlights the need for a multidisciplinary approach and emphasizes the value of culture and sensitivity testing in guiding effective treatment strategies.

摘要

葡萄球菌烫伤样皮肤综合征(SSSS)是一种主要影响儿童的严重剥脱性皮肤病,由金黄色葡萄球菌产生的毒素引起。本病例报告描述了一名儿科患者中合并耐甲氧西林金黄色葡萄球菌(MRSA)的SSSS的临床表现、诊断挑战及成功治疗。一名儿科患者有两周的瘙痒性水疱大疱性皮疹病史,且病情逐渐加重。尽管最初使用了包括类固醇和抗生素软膏在内的各种局部和口服药物进行治疗,但皮损仍继续进展。伤口培养发现大量MRSA生长,促使改变治疗方案,从而使临床症状显著改善。该病例强调了在SSSS治疗中准确诊断和及时干预的重要性,尤其是在合并MRSA时。适当抗生素治疗取得的成功结果凸显了多学科方法的必要性,并强调了培养和药敏试验在指导有效治疗策略方面的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b16/11619542/0e584efed090/JNMA-62-278-697-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b16/11619542/0e584efed090/JNMA-62-278-697-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b16/11619542/0e584efed090/JNMA-62-278-697-g1.jpg

相似文献

1
Pediatric Staphylococcal Scalded Skin Syndrome Complicated by Methicillin-Resistant Staphylococcus Aureus and Steroid Abuse: A Case Report.小儿葡萄球菌烫伤样皮肤综合征合并耐甲氧西林金黄色葡萄球菌感染及类固醇滥用:一例报告
JNMA J Nepal Med Assoc. 2024 Oct;62(278):697-699. doi: 10.31729/jnma.8770. Epub 2024 Oct 31.
2
Methicillin-resistant Staphylococcus aureus (MRSA) infection of the temple region of the face: Case report.面部颞部耐甲氧西林金黄色葡萄球菌(MRSA)感染:病例报告。
Medicine (Baltimore). 2025 Jun 13;104(24):e42824. doi: 10.1097/MD.0000000000042824.
3
Antimicrobial Resistance and Molecular Analysis of in Staphylococcal Scalded Skin Syndrome among Children in Korea.韩国儿童葡萄球菌性烫伤样皮肤综合征中 的耐药性及分子分析。
J Korean Med Sci. 2021 Jan 18;36(3):e22. doi: 10.3346/jkms.2021.36.e22.
4
Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.根除囊性纤维化患者体内耐甲氧西林金黄色葡萄球菌(MRSA)的干预措施。
Cochrane Database Syst Rev. 2018 Jul 21;7(7):CD009650. doi: 10.1002/14651858.CD009650.pub4.
5
Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant .噬菌体感染导致耐甲氧西林菌丧失β-内酰胺抗性 。
Elife. 2025 Jul 10;13:RP102743. doi: 10.7554/eLife.102743.
6
Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.针对囊性纤维化患者中耐甲氧西林金黄色葡萄球菌(MRSA)的清除干预措施。
Cochrane Database Syst Rev. 2022 Dec 13;12(12):CD009650. doi: 10.1002/14651858.CD009650.pub5.
7
Antibiotic prophylaxis for the prevention of methicillin-resistant Staphylococcus aureus (MRSA) related complications in surgical patients.用于预防外科手术患者耐甲氧西林金黄色葡萄球菌(MRSA)相关并发症的抗生素预防措施。
Cochrane Database Syst Rev. 2013 Aug 19;2013(8):CD010268. doi: 10.1002/14651858.CD010268.pub2.
8
Antimicrobial resistance and molecular characteristics of bovine mastitis-associated methicillin-resistant : potential for cross-species transmission of ST59-MRSA.牛乳腺炎相关耐甲氧西林菌的抗菌药物耐药性及分子特征:ST59-MRSA跨物种传播的可能性
Microbiol Spectr. 2025 Jul;13(7):e0280024. doi: 10.1128/spectrum.02800-24. Epub 2025 May 21.
9
Investigating the Prevalence of Enterotoxin and Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus (MRSA) Isolated From Meat and Edible Viscera of Broiler Chickens.调查从肉鸡的肉和可食用内脏中分离出的耐甲氧西林金黄色葡萄球菌(MRSA)中肠毒素的流行情况和抗生素耐药性。
Vet Med Sci. 2025 Jul;11(4):e70413. doi: 10.1002/vms3.70413.
10
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds.用于治疗非手术伤口耐甲氧西林金黄色葡萄球菌(MRSA)感染的抗生素疗法。
Cochrane Database Syst Rev. 2013 Nov 18;2013(11):CD010427. doi: 10.1002/14651858.CD010427.pub2.

本文引用的文献

1
[Staphylococcal scalded skin syndrom: a case report].[葡萄球菌性烫伤样皮肤综合征:一例报告]
Pan Afr Med J. 2021 Jul 6;39:177. doi: 10.11604/pamj.2021.39.177.22171. eCollection 2021.
2
Staphylococcal Scalded Skin Syndrome in Child. A Case Report and a Review from Literature.儿童葡萄球菌烫伤样皮肤综合征。一例病例报告及文献综述。
J Crit Care Med (Targu Mures). 2016 Nov 8;2(4):192-197. doi: 10.1515/jccm-2016-0028. eCollection 2016 Oct.
3
Staphylococcal scalded skin syndrome in a 4-year-old child: a case report.一名4岁儿童的葡萄球菌性烫伤样皮肤综合征:病例报告
J Med Case Rep. 2018 Jan 29;12(1):20. doi: 10.1186/s13256-017-1533-7.
4
Staphylococcal scalded skin syndrome: A pediatric dermatology case report.葡萄球菌性烫伤样皮肤综合征:一例儿科皮肤病病例报告。
SAGE Open Med Case Rep. 2018 Jan 4;6:2050313X17750890. doi: 10.1177/2050313X17750890. eCollection 2018.
5
Epidemiological data of staphylococcal scalded skin syndrome in France from 1997 to 2007 and microbiological characteristics of Staphylococcus aureus associated strains.法国 1997 年至 2007 年葡萄球菌性烫伤样皮肤综合征的流行病学数据和相关金黄色葡萄球菌菌株的微生物学特征。
Clin Microbiol Infect. 2012 Dec;18(12):E514-21. doi: 10.1111/1469-0691.12053. Epub 2012 Oct 19.
6
Adverse effects of topical glucocorticosteroids.外用糖皮质激素的不良反应。
J Am Acad Dermatol. 2006 Jan;54(1):1-15; quiz 16-8. doi: 10.1016/j.jaad.2005.01.010.
7
Staphylococcal scalded skin syndrome: diagnosis and management.葡萄球菌性烫伤样皮肤综合征:诊断与管理
Am J Clin Dermatol. 2003;4(3):165-75. doi: 10.2165/00128071-200304030-00003.
8
Clinical, microbial, and biochemical aspects of the exfoliative toxins causing staphylococcal scalded-skin syndrome.引起葡萄球菌烫伤样皮肤综合征的剥脱毒素的临床、微生物学及生物化学方面
Clin Microbiol Rev. 1999 Apr;12(2):224-42. doi: 10.1128/CMR.12.2.224.