Ashkar Laila, Abufarea Bashair M, Alkaeid Fai F, Alruwaithi Raghad O, Nadhra Raghad W
Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Medicine and Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Cureus. 2025 Jun 13;17(6):e85934. doi: 10.7759/cureus.85934. eCollection 2025 Jun.
This case presents a rare occurrence of ductal carcinoma in situ (DCIS) in a patient with a history of bilateral iatrogenic fat injections, aiming to contribute to the ongoing discussion on potential associations between fat grafting and breast pathology. A 43-year-old Saudi woman presented with bilateral palpable masses at the sites of previous fat grafting performed two years earlier. Despite having no significant risk factors or family history of breast cancer, imaging revealed a suspicious asymmetry adjacent to the palpable area in the left breast. Biopsy of this region confirmed fat necrosis with foci of atypical ductal hyperplasia and low-grade DCIS. This case underscores the importance of vigilant follow-up in patients undergoing autologous fat grafting to the breast.
该病例呈现了一名有双侧医源性脂肪注射史的患者罕见地发生了原位导管癌（DCIS），旨在为正在进行的关于脂肪移植与乳腺病理潜在关联的讨论提供参考。一名43岁的沙特女性在两年前进行过脂肪移植的部位出现双侧可触及肿块。尽管没有明显的危险因素或乳腺癌家族史，但影像学检查显示左乳可触及区域附近有可疑不对称。对该区域进行活检证实为脂肪坏死，伴有非典型导管增生灶和低级别DCIS。该病例强调了对接受自体脂肪移植到乳房的患者进行密切随访的重要性。
