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一名老年患者出现进行性截瘫,病因是胸段脊髓硬膜外血管脂肪瘤。

Thoracic spinal epidural angiolipoma presenting with progressive paraparesis in an elderly patient.

作者信息

Gok Haydar, Yangi Kivanc, Alomari Omar, Hacisalihoglu Uguray Payam

机构信息

Department of Neurosurgery, Yeni Yuzyıl University Gaziosmanpasa Hospital, İstanbul, Turkey.

Department of Neurosurgery, University of Health Sciences, Prof. Dr. Cemil Tascioglu City Hospital, İstanbul, Turkey.

出版信息

Surg Neurol Int. 2025 Jun 20;16:251. doi: 10.25259/SNI_389_2025. eCollection 2025.

Abstract

BACKGROUND

Spinal epidural angiolipomas (SEALs) are rare, benign tumors composed of mature adipocytes and abnormal vasculature, representing only 0.04-1.2% of spinal tumors. Predominantly located in the thoracic epidural space, they often cause progressive neurological deficits due to spinal cord compression, though acute deterioration may occur from hemorrhage or thrombosis. Misdiagnosis is common, and evidence-based management remains limited.

CASE DESCRIPTION

a 74-year-old woman presented with a 3-month history of progressive paraparesis, gait instability, and left-sided hyperreflexia. Spinal magnetic resonance ımaging revealed an 11 cm posterior epidural mass extending from T3 to T7, causing severe cord compression with myelopathic signal changes. The patient underwent T4-T6 laminectomy with gross total resection of the highly vascular mass. Histopathology confirmed the diagnosis of SEAL. Postoperatively, her symptoms improved, and she was discharged without complications.

CONCLUSION

This case highlights the importance of recognizing SEALs in differential diagnoses of spinal cord compression, emphasizing meticulous surgical excision for favorable outcomes. A literature review underscores the need for standardized management guidelines for these rare lesions.

摘要

背景

脊髓硬膜外血管脂肪瘤(SEALs)是一种罕见的良性肿瘤,由成熟的脂肪细胞和异常血管组成,仅占脊髓肿瘤的0.04 - 1.2%。它们主要位于胸段硬膜外间隙,常因脊髓受压导致进行性神经功能缺损,不过出血或血栓形成也可能导致急性病情恶化。误诊很常见,基于证据的治疗方法仍然有限。

病例描述

一名74岁女性,有3个月进行性双下肢轻瘫、步态不稳和左侧反射亢进的病史。脊髓磁共振成像显示一个11厘米的硬膜后肿块,从T3延伸至T7,导致严重的脊髓受压并伴有脊髓病变信号改变。患者接受了T4 - T6椎板切除术,并对高度血管化的肿块进行了全切。组织病理学确诊为SEAL。术后,她的症状有所改善,出院时无并发症。

结论

本病例强调了在脊髓压迫的鉴别诊断中识别SEALs的重要性,强调精心的手术切除以获得良好的治疗效果。文献综述强调了针对这些罕见病变制定标准化管理指南的必要性。

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