Bitra Jyotsna, Sureshkumar Haarisudhan, Eathara Abhijith V, Alahmadi Reem, Heiferman Michael J
Department of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, IL, USA.
Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
J Vitreoretin Dis. 2025 Jul 8:24741264251351545. doi: 10.1177/24741264251351545.
To report the incidence of and risk factors associated with recurrent vitreous hemorrhage (VH) in eyes that had 25-gauge pars plana vitrectomy (PPV) for proliferative diabetic retinopathy (PDR). This study included 220 eyes of 185 patients who were 21 years old or older and who had PPV for PDR and a minimum postoperative follow-up of 3 months. For patients who had bilateral PPV, data were gathered from both eyes. If surgery was performed in only 1 eye, data were collected from that eye alone. The incidence of recurrent VH was 34.5% (76 eyes). The VH was categorized as early in 46 eyes (60.5%), delayed in 8 eyes (10.5%), or late in 22 eyes (28.9%). Sixty-eight eyes (89.5%) had mild/moderate recurrent VH and 8 (10.5%) had severe recurrent VH. The mean preoperative fasting blood glucose level was 147.7 mg/dL in eyes without recurrent VH and 176.7 mg/dL in eyes with recurrent VH ( = .020). Younger age ( = .027) and higher diastolic blood pressure at the time of surgery ( = .005) also significantly affected recurrent VH. Younger age, preoperative fasting blood glucose levels, and diastolic blood pressure were significantly associated with recurrent VH after PPV in patients with PDR.
报告接受25G玻璃体切割术（PPV）治疗增生性糖尿病视网膜病变（PDR）的患眼中复发性玻璃体出血（VH）的发生率及相关危险因素。本研究纳入了185例年龄在21岁及以上、因PDR接受PPV且术后至少随访3个月的患者的220只眼。对于接受双侧PPV的患者，双眼均收集数据。若仅一只眼进行了手术，则仅收集该眼的数据。复发性VH的发生率为34.5%（76只眼）。VH被分类为早期46只眼（60.5%）、延迟性8只眼（10.5%）或晚期22只眼（28.9%）。68只眼（89.5%）发生轻度/中度复发性VH，8只眼（10.5%）发生重度复发性VH。无复发性VH的患眼术前空腹血糖平均水平为147. mg/dL，有复发性VH的患眼为176.7 mg/dL（P = 0.020）。年龄较轻（P = 0.027）以及手术时较高的舒张压（P = 0.005）也对复发性VH有显著影响。年龄较轻、术前空腹血糖水平及舒张压与PDR患者PPV术后复发性VH显著相关。
