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美国脊柱手术后家庭收入作为手术结果和阿片类药物使用的预测指标

Household Income as a Predictor for Surgical Outcomes and Opioid Use After Spine Surgery in the United States.

作者信息

Barrie Umaru, Montgomery Eric Y, Ogwumike Erica, Pernik Mark N, Luu Ivan Y, Adeyemo Emmanuel A, Christian Zachary K, Edukugho Derrek, Johnson Zachary D, Hoes Kathryn, El Tecle Najib, Hall Kristen, Aoun Salah G, Bagley Carlos A

机构信息

Department of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.

Department of Neurological Surgery, Boonshoft School of Medicine, Wright State University, Dayton, OH, USA.

出版信息

Global Spine J. 2023 Oct;13(8):2124-2134. doi: 10.1177/21925682211070823. Epub 2022 Jan 10.

Abstract

STUDY DESIGN

Cross-Sectional Study.

OBJECTIVES

Socioeconomic status (SES) is a fundamental root of health disparities, however, its effect on surgical outcomes is often difficult to capture in clinical research, especially in spine surgery. Here, we present a large single-center study assessing whether SES is associated with cause-specific surgical outcomes.

METHODS

Patients undergoing spine surgery between 2015 and 2019 were assigned income in accordance with the national distribution and divided into quartiles based on the ZIP code-level median household income. We performed univariate, chi-square, and Analysis of Variance (ANOVA) analysis assessing the independent association of SES, quantified by household income, to operative outcomes, and multiple metrics of opioid consumption.

RESULTS

1199 patients were enrolled, and 1138 patients were included in the analysis. Low household income was associated with the greatest rates of 3-month opioid script renewal (OR:1.65, 95% CI:1.14-2.40). In addition, low-income was associated with higher rates of perioperative opioid consumption compared to higher income including increased mean total morphine milligram equivalent (MME) 252.25 (SD 901.32) vs 131.57 (SD 197.46) (P < .046), and inpatient IV patient-controlled analgesia (PCA) MME 121.11 (SD 142.14) vs 87.60 (SD 86.33) (P < .023). In addition, household income was independently associated with length of stay (LOS), and emergency room (ER) revisits with low-income patients demonstrating significantly longer postop LOS and increasing postoperative ER visits.

CONCLUSIONS

Considering the comparable surgical management provided by the single institution, the associated differences in postoperative outcomes as defined by increased morbidities and opioid consumption can potentially be attributed to health disparities caused by SES.

摘要

研究设计

横断面研究。

目的

社会经济地位(SES)是健康差异的一个基本根源,然而,其对外科手术结果的影响在临床研究中往往难以捕捉,尤其是在脊柱外科手术中。在此,我们开展了一项大型单中心研究,评估SES是否与特定病因的手术结果相关。

方法

2015年至2019年间接受脊柱手术的患者根据全国分布情况被赋予收入,并根据邮政编码级别的家庭收入中位数分为四分位数。我们进行了单变量、卡方和方差分析(ANOVA),评估以家庭收入量化的SES与手术结果以及多种阿片类药物消费指标之间的独立关联。

结果

共纳入1199例患者,1138例患者纳入分析。低家庭收入与3个月阿片类药物处方续签率最高相关(比值比:1.65,95%置信区间:1.14 - 2.40)。此外,与高收入相比,低收入与围手术期阿片类药物消费率较高相关,包括平均总吗啡毫克当量(MME)增加,分别为252.25(标准差901.32)对131.57(标准差197.46)(P <.046),以及住院患者静脉自控镇痛(PCA)的MME分别为121.11(标准差142.14)对87.60(标准差86.33)(P <.023)。此外,家庭收入与住院时间(LOS)以及急诊室(ER)复诊独立相关,低收入患者术后LOS明显更长,术后ER复诊次数增加。

结论

考虑到单一机构提供的可比手术管理,发病率增加和阿片类药物消费所定义的术后结果的相关差异可能归因于SES导致的健康差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/664d/10538313/d4b693b17247/10.1177_21925682211070823-fig1.jpg

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