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坦桑尼亚的新冠疫苗接种情况及社会经济差异:一项在高度犹豫背景下基于人群的横断面研究

COVID-19 Vaccine Uptake and Socioeconomic Disparities in Tanzania: A Population-Based Cross-Sectional Study Amid High Hesitancy.

作者信息

Bintabara Deogratius, Mchonde Gabriel

机构信息

Department of Community Medicine The University of Dodoma Dodoma Tanzania.

Department of Anatomy and Histology, School of Medicine and Dentistry The University of Dodoma Dodoma Tanzania.

出版信息

Health Sci Rep. 2025 Jul 11;8(7):e71044. doi: 10.1002/hsr2.71044. eCollection 2025 Jul.

DOI:10.1002/hsr2.71044
PMID:40657298
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12246958/
Abstract

BACKGROUND AND AIMS

Socioeconomic disparities in healthcare access, including vaccination services, persist worldwide. The COVID-19 pandemic amplified these disparities, particularly in low-resource settings such as Tanzania, where vaccine hesitancy remains a significant challenge. Understanding these disparities is crucial for achieving equitable vaccine coverage. This study assessed regional variations in socioeconomic disparities in COVID-19 vaccine uptake in Tanzania, with education used as a proxy for socioeconomic status. The findings aim to guide targeted interventions for populations facing greater disadvantages.

METHODS

A population-based cross-sectional survey was conducted between June and July 2022, involving 22,910 adults from urban areas in Mwanza, Iringa, Arusha, and Morogoro regions. Participants were selected using cluster sampling. Vaccine uptake, defined as receiving any complete dose of the COVID-19 vaccine, was the primary outcome. Disparities were analyzed using concentration curves and indices, while multivariable logistic regression identified factors contributing to these disparities.

RESULTS

Of the respondents, approximately 20% were fully vaccinated. Significant educational disparities favoring the educated were observed, with the most pronounced gaps in Mwanza (CI: 0.093,  < 0.001) and Arusha (CI: 0.062,  < 0.001) compared to Iringa (CI: 0.011,  < 0.01) and Morogoro (CI: 0.040,  < 0.001). Multivariable analysis identified age, marital status, occupation, and knowledge as potential factors associated with vaccine uptake disparities. Educated individuals were significantly more likely to be vaccinated, underscoring the role of education in shaping vaccine access and acceptance.

CONCLUSIONS

This study highlights the need to address regional and socioeconomic disparities in COVID-19 vaccine uptake in Tanzania. Tailored policies that consider education levels, employment type, and community perceptions are essential to improving vaccine coverage. Efforts must focus on reducing hesitancy and promoting equitable access, particularly among disadvantaged groups.

摘要

背景与目的

包括疫苗接种服务在内的医疗保健可及性方面的社会经济差异在全球范围内持续存在。新冠疫情加剧了这些差异,在坦桑尼亚等资源匮乏地区尤为明显,在这些地区,疫苗犹豫仍然是一项重大挑战。了解这些差异对于实现公平的疫苗接种覆盖率至关重要。本研究评估了坦桑尼亚新冠疫苗接种中社会经济差异的地区差异,以教育程度作为社会经济地位的替代指标。研究结果旨在指导针对面临更大劣势人群的有针对性干预措施。

方法

2022年6月至7月进行了一项基于人群的横断面调查,涉及来自姆万扎、伊林加、阿鲁沙和莫罗戈罗地区城市地区的22910名成年人。参与者采用整群抽样法选取。疫苗接种率定义为接种任何一剂完整的新冠疫苗,是主要结果。使用集中曲线和指数分析差异,同时多变量逻辑回归确定导致这些差异的因素。

结果

在受访者中,约20%的人完成了全程接种。观察到明显有利于受过教育者的教育差异,与伊林加(置信区间:0.011,<0.01)和莫罗戈罗(置信区间:0.040,<0.001)相比,姆万扎(置信区间:0.093,<0.001)和阿鲁沙(置信区间:0.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/82382dcfb5da/HSR2-8-e71044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/c262dc724132/HSR2-8-e71044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/da54aa4472ea/HSR2-8-e71044-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/82382dcfb5da/HSR2-8-e71044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/c262dc724132/HSR2-8-e71044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/da54aa4472ea/HSR2-8-e71044-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c778/12246958/82382dcfb5da/HSR2-8-e71044-g003.jpg

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本文引用的文献

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