Rašić Dejan M, Vasović Dolika D, Knežević Miroslav
Eye Hospital, University Clinical Centre of Serbia, Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Case Rep Ophthalmol Med. 2025 Jun 27;2025:5032089. doi: 10.1155/crop/5032089. eCollection 2025.
This case report describes a rare instance of primary orbital teratoma with anophthalmia in a neonate. A 6-day-old female presented with a congenital right orbital swelling and absence of visible ocular structures. MRI revealed a large, well-vascularized orbital mass without intracranial extension, accompanied by malformations in the right cerebral hemisphere. Histopathological examination confirmed a benign, mature/mixed teratoma comprising elements from all three germ layers, including neuroectoderm, mesoderm, and endoderm, with no evidence of malignancy. The patient underwent successful orbital exenteration with an implant at 3 weeks of age.
本病例报告描述了一例罕见的新生儿原发性眼眶畸胎瘤伴无眼球症。一名6日龄女婴出现先天性右眼眶肿胀且未见可见眼部结构。磁共振成像（MRI）显示一个大的、血管丰富的眼眶肿物，无颅内扩展，同时伴有右侧大脑半球畸形。组织病理学检查证实为良性、成熟/混合性畸胎瘤，包含来自所有三个胚层的成分，即神经外胚层、中胚层和内胚层，无恶性证据。该患者在3周龄时成功接受了眼眶内容剜除术并植入了假体。
