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一位老年重症支气管扩张症患者的麻醉管理

Anesthetic Management for an Elderly Patient With Severe Bronchiectasis.

作者信息

Takahashi Tamayo, Yoshida Mitsuhiro, Ito Nanako, Koizumi Koichi, Kamio Hisanobu, Oda Aya, Oue Kana, Doi Mitsuru, Shimizu Yoshitaka

出版信息

Anesth Prog. 2025 Mar 12;72(1):33-36. doi: 10.2344/23-0036.

DOI:10.2344/23-0036
PMID:40657835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11922515/
Abstract

Bronchiectasis is a clinical syndrome characterized by coughing and sputum production in the presence of abnormal thickening and dilatation of the bronchial walls. We report the successful anesthetic management of a 91-year-old patient with severe bronchiectasis undergoing left marginal mandibulectomy for squamous cell carcinoma of the mandibular gingiva. In this case, we utilized respiratory prehabilitation for preoperative optimization of the patient's respiratory function and intravenous moderate sedation with dexmedetomidine and pentazocine plus excellent local anesthesia intraoperatively rather than an intubated general anesthetic. During the procedure, the patient's vital signs were stable, and she did not have any psychological or physical complaints like anxiety or pain and was discharged from the hospital without any complications. Considering the high risk of respiratory complications, intravenous moderate sedation may be a better option than general anesthesia for some surgeries in patients with severe bronchiectasis. These strategies may be useful options for older patients with impaired respiratory function undergoing oral surgery procedures.

摘要

支气管扩张症是一种临床综合征,其特征为在存在支气管壁异常增厚和扩张的情况下出现咳嗽和咳痰。我们报告了一例91岁患有严重支气管扩张症的患者,该患者因下颌牙龈鳞状细胞癌接受左下颌边缘切除术,其麻醉管理取得成功。在本病例中,我们采用呼吸预康复来术前优化患者的呼吸功能,并在术中使用右美托咪定和喷他佐辛进行静脉中度镇静以及出色的局部麻醉,而非插管全身麻醉。手术过程中,患者生命体征稳定,没有出现任何如焦虑或疼痛等心理或身体不适,且出院时无任何并发症。考虑到呼吸并发症的高风险,对于一些患有严重支气管扩张症的患者进行手术,静脉中度镇静可能是比全身麻醉更好的选择。这些策略对于呼吸功能受损的老年患者接受口腔外科手术可能是有用的选择。

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本文引用的文献

1
Analgesia-based Sedation for Oral Surgery in Patients With Chronic Respiratory Obstructive Disease.
J Craniofac Surg. 2023;34(1):e70-e74. doi: 10.1097/SCS.0000000000009004. Epub 2022 Sep 14.
2
Dexmedetomidine for prevention of postoperative pulmonary complications in patients after oral and maxillofacial surgery with fibular free flap reconstruction:a prospective, double-blind, randomized, placebo-controlled trial.右美托咪定预防口腔颌面部手术游离腓骨瓣重建术后肺部并发症的前瞻性、双盲、随机、安慰剂对照试验。
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Comparision of Vital Surgical Parameters, after Administration of Midazolam and Dexmedetomidine for Conscious Sedation in Minor Oral Surgery.咪达唑仑和右美托咪定用于小型口腔手术清醒镇静后的重要手术参数比较
Ann Maxillofac Surg. 2019 Jul-Dec;9(2):283-288. doi: 10.4103/ams.ams_17_19.
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Conscious Sedation in Dentistry.牙科镇静
Medicina (Kaunas). 2019 Dec 7;55(12):778. doi: 10.3390/medicina55120778.
5
Bronchiectasis.支气管扩张症。
Nat Rev Dis Primers. 2018 Nov 15;4(1):45. doi: 10.1038/s41572-018-0042-3.
6
European Respiratory Society guidelines for the management of adult bronchiectasis.欧洲呼吸学会成人支气管扩张症管理指南。
Eur Respir J. 2017 Sep 9;50(3). doi: 10.1183/13993003.00629-2017. Print 2017 Sep.
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The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review.ICU 中主动活动和康复治疗对死亡率和功能的影响:系统评价。
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Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial.早期目标导向性外科重症监护病房中的患者活动:一项随机对照试验。
Lancet. 2016 Oct 1;388(10052):1377-1388. doi: 10.1016/S0140-6736(16)31637-3.
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Pulmonary Rehabilitation in Individuals With Non-Cystic Fibrosis Bronchiectasis: A Systematic Review.非囊性纤维化支气管扩张症患者的肺康复:一项系统评价
Arch Phys Med Rehabil. 2017 Apr;98(4):774-782.e1. doi: 10.1016/j.apmr.2016.05.017. Epub 2016 Jun 16.
10
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.右美托咪定:在重症监护环境中镇静的应用综述。
Drugs. 2015 Jul;75(10):1119-30. doi: 10.1007/s40265-015-0419-5.