Unusual Locations of Extra-Glossal Ectomesenchymal Chondromyxoid Tumors with RREB1-MRTFB Gene Fusions: A Report of Two Cases.

INTRODUCTION

Ectomesenchymal chondromyxoid tumor (EMCMT) is a rare benign tumor of the oral cavity that nearly always occurs in the anterior dorsal aspect of the tongue and has an indolent clinical course. Most EMCMTs harbor a RREB1-MRTFB rearrangement.

MATERIALS AND METHODS

We report two cases of extra-glossal EMCMTs with RREB1-MRTFB fusions, one being the first from the sinonasal tract to be described.

CONCLUSION

In addition to other reported extra-glossal tumors harboring RREB1-MRTFB fusions, our cases expand the spectrum of tumors carrying this rearrangement and raise awareness for extra-glossal locations of EMCMTs.