Zhu Zhenggang, Kitayama Joji, Kim Hyung-Ho, So Jimmy Bok-Yan, Cao Hui, Chen Lin, Cheng Xiangdong, Hu Jiankun, Imano Motohiro, Ishigami Hironori, Jee Ye Seob, Kim Jong-Han, Kodera Yasuhiro, Liang Han, Liu Xiaowen, Lu Sheng, Mou Yiping, Nie Mingming, Seo Won Jun, Wang Yanong, Wu Dan, Xu Zekuan, Yamaguchi Hironori, Yan Chao, Yang Zhongyin, Yin Kai, Yonemura Yutaka, Yong Wei-Peng, Yu Jiren, Zhang Jun
Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China.
Department of Gastrointestinal Surgery, Clinical Research Center, Jichi Medical University, Jichi Medical University Hospital, Shimotsuke, Japan.
Gastric Cancer. 2025 Jul 14. doi: 10.1007/s10120-025-01631-9.
Peritoneal metastasis (PM) is a major challenge in advanced gastric cancer (GC) with poor prognosis. Normothermic intraperitoneal and systemic treatment (NIPS) has become a promising therapeutic approach. This consensus aims to provide practical recommendations for NIPS treatment for gastric cancer with peritoneal metastasis (GCPM). The GRADE standards were used to rank evidence, and the Delphi method was employed for expert voting. 30 experts from China, Japan, South Korea, and Singapore participated in the development of this consensus. 28 experts participated in the voting process, which produced 29 statements covering diagnostic approaches, patient selection criteria, treatment regimens, management of intraperitoneal port placement, and conversion surgery considerations, and post-surgical treatment strategies in NIPS therapy. Based on current evidence and expert experience, these statements aim to improve the clinical outcomes of NIPS therapy for GCPM patients.
腹膜转移（PM）是晚期胃癌（GC）面临的一项重大挑战，预后较差。常温下腹腔及全身治疗（NIPS）已成为一种有前景的治疗方法。本共识旨在为伴有腹膜转移的胃癌（GCPM）的NIPS治疗提供实用建议。采用GRADE标准对证据进行分级，并运用德尔菲法进行专家投票。来自中国、日本、韩国和新加坡的30位专家参与了本共识的制定。28位专家参与了投票过程，产生了29条声明，涵盖诊断方法、患者选择标准、治疗方案、腹腔端口置入管理、转化手术考量以及NIPS治疗中的术后治疗策略。基于当前证据和专家经验，这些声明旨在改善GCPM患者NIPS治疗的临床结局。
