缺铁可保护近交系小鼠免受查巴迪疟原虫的感染。
Iron deficiency protects inbred mice against infection with Plasmodium chabaudi.
作者信息
Harvey P W, Bell R G, Nesheim M C
出版信息
Infect Immun. 1985 Dec;50(3):932-4. doi: 10.1128/iai.50.3.932-934.1985.
Abstract
Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.
摘要
通过饮食缺铁导致贫血的NFR/N小鼠感染查巴迪疟原虫后，死亡率为25%（雄性）和7%（雌性），而铁充足的对照组死亡率为100%。当从初次感染中恢复的缺铁小鼠恢复正常饮食时，100%出现复发寄生虫血症。维持缺铁饮食的小鼠未出现复发。
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本文引用的文献
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