Kraeft H, Roos R, Mrozik E
Infection. 1985 Sep-Oct;13(5):211-5. doi: 10.1007/BF01667213.
Quantitative bacterial counts were carried out on 161 gastric aspirates of 65 neonates with gastrostomy. In comparison to 101 controls--cultures of premature infants without gastrostomy--Enterobacteriaceae, enterococci, Pseudomonas and Candida were found far more frequently (p less than 0.01). The colonization of the stomach was influenced by the duration of gastrostomy and by the pH of the gastric juice but not by systemic antibiotic therapy or the kind of food. Six newborns with gastrostomy developed septicaemia caused by the same organisms as we had found in elevated numbers in their gastric aspirates. The influence of non-absorbable antibiotics was studied prospectively in 72 gastric aspirates and 48 stool specimens. There was no highly significant difference between infants who had been treated with these antibiotics and those who had not.
对65例接受胃造口术的新生儿的161份胃吸出物进行了细菌定量计数。与101例对照（未行胃造口术的早产儿培养物）相比，肠杆菌科、肠球菌、假单胞菌和念珠菌的检出频率要高得多（p<0.01）。胃的定植受胃造口术持续时间和胃液pH值的影响，但不受全身抗生素治疗或食物种类的影响。6例接受胃造口术的新生儿发生败血症，病原菌与在他们胃吸出物中数量增多的病原菌相同。对72份胃吸出物和48份粪便标本进行前瞻性研究，观察不可吸收抗生素的影响。接受这些抗生素治疗的婴儿与未接受治疗的婴儿之间没有高度显著差异。
