Greve E L, Dake C L, Klaver J H, Mutsaerts E M
Int Ophthalmol. 1985 Sep;8(3):139-46. doi: 10.1007/BF00136490.
The results of a longterm prospective follow-up study after the 'Double Flap' Scheie filtering operation are presented. Fifty-two eyes of 47 patients with primary open angle glaucoma (POAG) were operated; after ten years 29 eyes of 24 patients could be examined. Twenty patients (43%) had died, in three follow-up was incomplete. The two and four year results have been published earlier. In the 29 eyes the mean intraocular pressure (IOP) without medical therapy rose from 15.8 mm Hg at five years to 16.3 mm Hg at ten years (not significant). Additional medical or surgical treatment was necessary in 35% of the eyes. Diurnal variation and outflow facility remained stable. During the ten years 13 eyes showed some deterioration of visual fields. Nearly all clinically important deterioration occurred within five years after the operation. Cataract progression was noticed in 45% (13 of 29); four times a lens extraction was performed (13%). Complete success of the operation, as judged by stable visual fields and IOP levels at or under 21 mm Hg without additional medical or surgical therapy was reached in 13 of 20 eyes (45%). Based on IOP alone the success rate was 62% without and 93% with additional treatment.
本文介绍了“双瓣”Scheie滤过手术后的长期前瞻性随访研究结果。对47例原发性开角型青光眼（POAG）患者的52只眼进行了手术；10年后，对24例患者的29只眼进行了检查。20例患者（43%）死亡，3例随访不完全。两年和四年的结果已在之前发表。在这29只眼中，未经药物治疗时的平均眼压（IOP）从5年时的15.8 mmHg升至10年时的16.3 mmHg（无显著差异）。35%的眼需要额外的药物或手术治疗。眼压日波动和房水流出易度保持稳定。在这10年中，13只眼的视野出现了一些恶化。几乎所有具有临床意义的恶化都发生在手术后5年内。45%（29只眼中的13只）出现了白内障进展；进行了4次晶状体摘除术（13%）。根据视野稳定且眼压在21 mmHg或以下且无需额外药物或手术治疗来判断，20只眼中有13只（45%）手术完全成功。仅基于眼压，未进行额外治疗时成功率为62%，进行额外治疗时为93%。
