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男性人乳头瘤病毒检测的必要性与挑战

The necessity and challenges of human papillomavirus testing for men.

作者信息

Ren Wenbo, Jin Yuting, Shi Lin, Chen Haizhen, Zhang Zichen, Wang Yifei, Zhai Taiyu, Huang Jing

机构信息

Department of Clinical Laboratory, The First Hospital of Jilin University, Changchun, China.

College of Medical Technology, Beihua University, Jilin, China.

出版信息

Front Cell Infect Microbiol. 2025 Jun 30;15:1563499. doi: 10.3389/fcimb.2025.1563499. eCollection 2025.

Abstract

Beyond its historical association with cervical cancer in women, human papillomavirus (HPV) infection poses a widespread health concern, particularly for men. Recent studies have highlighted the prevalence of HPV-related cancers, including penile and anal cancers, among the male population, making the case for male HPV testing all the more compelling. The potential for cross-infection between sexual partners underscores the need for comprehensive screening strategies. However, challenges still remain, such as the limited availability of testing methods and the absence of uniform medical guidelines, hampering effective HPV detection in men. Addressing these challenges through intensified research efforts and the revision of medical guidelines is crucial to enhancing prevention strategies and unlocking significant public health benefits.

摘要

除了其在历史上与女性宫颈癌的关联外,人乳头瘤病毒(HPV)感染引发了广泛的健康问题,尤其是对男性而言。最近的研究凸显了男性人群中HPV相关癌症(包括阴茎癌和肛门癌)的患病率,这使得男性HPV检测的必要性更加迫切。性伴侣之间交叉感染的可能性凸显了全面筛查策略的必要性。然而,挑战依然存在,比如检测方法有限以及缺乏统一的医学指南,这阻碍了对男性进行有效的HPV检测。通过加大研究力度和修订医学指南来应对这些挑战,对于加强预防策略和实现显著的公共卫生效益至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5db/12256477/2cf4295292c5/fcimb-15-1563499-g001.jpg

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