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儿童面部毛母质瘤:一种罕见的软组织病变鉴别诊断。

Facial Pilomatrixoma in a Child: A Rare Differential for a Soft Tissue Lesion.

作者信息

Saleem Muhammad Mudasir, Pervaiz Mishal, Shoaib Uswah, Mazhar Ismail, Rai Mir Muhammad, Rehman Saeed Ur, Ul Aaien Kurrat, Ur Rehman Syed Atta

机构信息

Pediatric and General Surgery, Combined Military Hospital, Lahore, PAK.

Anesthesiology, Punjab Rangers Teaching Hospital, Lahore, PAK.

出版信息

Cureus. 2025 Jun 14;17(6):e85989. doi: 10.7759/cureus.85989. eCollection 2025 Jun.

Abstract

Pilomatrixoma is an uncommon benign skin tumor originating from hair matrix cells, most frequently observed in children. Due to its slow growth and nonspecific presentation, it is often misdiagnosed as other skin or soft tissue lesions. A high index of suspicion is crucial for early recognition and appropriate management. We report the case of an eight-year-old boy who presented with a gradually enlarging, firm, non-tender, mobile swelling on the right cheek over two years. The mass, located anterior and slightly inferior to the right ear near the angle of the mandible, had no associated history of trauma or systemic illness. Surgical excision under general anesthesia was performed. Histopathological examination confirmed the diagnosis of pilomatrixoma. No preoperative imaging was performed, as clinical assessment favored a benign superficial lesion. The patient recovered uneventfully, and no recurrence was observed during a six-month postoperative follow-up. This case underscores the importance of including pilomatrixoma in the differential diagnosis of pediatric facial masses. While our follow-up duration was limited to six months, no signs of recurrence were noted during that period. Timely clinical recognition and complete surgical excision generally yield excellent outcomes, although longer-term surveillance is ideal.

摘要

毛发上皮瘤是一种罕见的起源于毛母质细胞的良性皮肤肿瘤,多见于儿童。由于其生长缓慢且表现不具特异性,常被误诊为其他皮肤或软组织病变。高度的怀疑指数对于早期识别和恰当处理至关重要。我们报告一例8岁男孩的病例,其右侧脸颊出现一个逐渐增大、质地坚硬、无压痛、可活动的肿物,持续两年时间。该肿物位于右耳前方、下颌角附近且略偏下,无相关外伤史或全身性疾病史。在全身麻醉下进行了手术切除。组织病理学检查确诊为毛发上皮瘤。由于临床评估倾向于良性浅表病变,故未进行术前影像学检查。患者恢复顺利,术后6个月随访期间未观察到复发。该病例强调了在小儿面部肿物的鉴别诊断中纳入毛发上皮瘤的重要性。虽然我们的随访时间仅限于6个月,但在此期间未发现复发迹象。尽管长期监测是理想的,但及时的临床识别和完整的手术切除通常会产生良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daad/12257570/4ae9c63dbc24/cureus-0017-00000085989-i01.jpg

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本文引用的文献

2
Multiple Postvaccinal Pilomatrixomas in a Child.
Clin Pediatr (Phila). 2023 Jul;62(7):692-694. doi: 10.1177/00099228221144941. Epub 2022 Dec 15.
3
Syndromes associated with multiple pilomatricomas: When should clinicians be concerned?
Pediatr Dermatol. 2020 Jan;37(1):9-17. doi: 10.1111/pde.13947. Epub 2019 Oct 16.
4
Pilomatrixoma: A Comprehensive Review of the Literature.
Am J Dermatopathol. 2018 Sep;40(9):631-641. doi: 10.1097/DAD.0000000000001118.
6
Pilomatrix carcinoma: More malignant biological behavior than was considered in the past.
Mol Clin Oncol. 2017 Mar;6(3):415-418. doi: 10.3892/mco.2017.1148. Epub 2017 Feb 2.
7
Giant pilomatricoma (pilomatrixoma) following an intramuscular injection.
J Dermatol Case Rep. 2008 Mar 29;2(1):11-3. doi: 10.3315/jdcr.2008.1005.
8
Pilomatrixoma. Review of 205 cases.
Med Oral Patol Oral Cir Bucal. 2011 Jul 1;16(4):e552-5. doi: 10.4317/medoral.16.e552.
9
Pilomatricoma arising at a BCG vaccination site.
Clin Exp Dermatol. 2006 Mar;31(2):296-7. doi: 10.1111/j.1365-2230.2005.02016.x.
10
Pilomatrixoma: a review of 346 cases.
Plast Reconstr Surg. 2003 Dec;112(7):1784-9. doi: 10.1097/01.PRS.0000091160.54278.64.

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