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撤稿声明:前列腺癌细胞中Epac1诱导的细胞增殖由B-Raf/ERK和mTOR信号级联介导。

RETRACTION: Epac1-Induced Cellular Proliferation in Prostate Cancer Cells Is Mediated by B-Raf/ERK and mTOR Signaling Cascades.

出版信息

J Cell Biochem. 2025 Jul;126(7):e70046. doi: 10.1002/jcb.70046.

DOI:10.1002/jcb.70046
PMID:40662249
Abstract

U. K. Misra and S. V. Pizzo, "Epac1-Induced Cellular Proliferation in Prostate Cancer Cells Is Mediated by B-Raf/ERK and mTOR Signaling Cascades," Journal of Cellular Biochemistry 108, no. 4 (2009): 998-1011, https://doi.org/10.1002/jcb.22333. The above article, published online on 1 September 2009 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties. Specifically, duplication of image elements has been detected between Figures 2A and 4B, between Figure 3B and 3D, and between Figures 3B and 4C. In all instances, these image elements have been used to represent different experimental conditions. An institutional review confirmed the validity of the concerns. Accordingly, the article is retracted as the editors have lost trust in the accuracy and integrity of the whole body of data and consider the conclusions of the article invalid. The authors have been informed of the decision of retraction.

摘要

英国的米斯拉(U. K. Misra)和皮佐(S. V. Pizzo)所著的《Epac1诱导前列腺癌细胞增殖由B-Raf/ERK和mTOR信号级联介导》,发表于《细胞生物化学杂志》第108卷,第4期(2009年),第998 - 1011页,https://doi.org/10.1002/jcb.22333 。上述文章于2009年9月1日在威利在线图书馆(wileyonlinelibrary.com)在线发表,现已根据期刊主编克里斯蒂安·贝尔(Christian Behl)与威利期刊有限责任公司达成的协议撤回。撤回是由于第三方提出的担忧。具体而言,已检测到图2A与图4B之间、图3B与图3D之间以及图3B与图4C之间存在图像元素重复。在所有这些情况下,这些图像元素被用于表示不同的实验条件。一项机构审查证实了这些担忧的合理性。因此,该文章被撤回,因为编辑们对整个数据集的准确性和完整性失去了信任,并认为该文章的结论无效。已将撤回决定告知作者。

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