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撤稿声明:P210 Bcr-abl酪氨酸激酶与组蛋白去乙酰化酶1的相互作用改变慢性髓性白血病造血祖细胞的组蛋白H4乙酰化和染色质结构。

RETRACTION: P210 Bcr-abl Tyrosine Kinase Interaction with Histone Deacetylase 1 Modifies Histone H4 Acetylation and Chromatin Structure of Chronic Myeloid Leukaemia Haematopoietic Progenitors.

出版信息

Br J Haematol. 2025 Jul;207(1):319. doi: 10.1111/bjh.20188. Epub 2025 May 26.

Abstract

G. Brusa, E. Zuffa, M. Mancini, M. Benvenuti, N. Calonghi, E. Barbieri, and M. A. Santucci, "P210 Bcr-abl Tyrosine Kinase Interaction with Histone Deacetylase 1 Modifies Histone H4 Acetylation and Chromatin Structure of Chronic Myeloid Leukaemia Haematopoietic Progenitors," British Journal of Haematology 132, no. 3 (2006): 359-369, https://doi.org/10.1111/j.1365-2141.2005.05873.x. The above article, published online on 29 November 2005 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief Andrew Evens; the British Society for Haematology; and John Wiley & Sons Ltd. A third party notified the journal that they had found evidence of image manipulation and duplication within Figures 4, and 5. The third party also reported that bands in Figure 4 of this article had been reused in 2 other articles by some of the same authors (Mancini et al. 2007 [https://doi.org/10.1016/j.leukres.2006.09.022] and Mancini et al. 2008 [https://doi.org/10.1111/j.1365-2141.2008.07134.x]). An investigation by the publisher confirmed that two Histone H1 bands in Figure 4 had been duplicated, 2 Histone H4 bands in Figure 5B had been duplicated, and that the bcr-abl bands in Figure 5B had been spliced and potentially duplicated. The investigation also confirmed that bands had been reused in other articles by the same authors, each of which describes different experimental conditions. Authors M. Mancini and N. Calonghi responded to an inquiry by the publisher, but due to the length of time since publication they were not able to provide an explanation for the evidence of image manipulation or the original data. The authors did not respond to our notice regarding the retraction.

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