Makanjuola R O, Hill G, Maben I, Dow R C, Ashcroft G W
Psychopharmacology (Berl). 1977 May 9;52(3):271-7. doi: 10.1007/BF00426711.
A technique is described for studying exploratory as well as stereotyped behaviour in rats using an automated hole-board. Both visual and automated recordings can be employed using the technique. Hole dipping is monitored automatically using an infra-red detector system. Repetitive patterns of hole-dipping are used as parameters of stereotyped behaviour while the more random patterns of hole-dipping are used as parameters of exploration. There was a high significant correlation between the records of hole-dipping behaviour as recorded visually and automatically. There was also a high significant correlation between the measures of repetitiveness/randomness of hole-dipping behaviour from automatic and visual recordings. The pattern and levels of hole-dipping conformed with expectations both as regards changes with time and with increasing doses of dl-amphetamine.
描述了一种使用自动孔板研究大鼠探索行为和刻板行为的技术。该技术可同时进行视觉记录和自动记录。使用红外探测器系统自动监测孔蘸行为。孔蘸的重复模式用作刻板行为的参数,而更随机的孔蘸模式用作探索的参数。视觉记录和自动记录的孔蘸行为记录之间存在高度显著的相关性。自动记录和视觉记录的孔蘸行为的重复性/随机性测量之间也存在高度显著的相关性。孔蘸的模式和水平在随时间变化以及随着dl-苯丙胺剂量增加方面均符合预期。