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Metabolic and fermentation engineering of Klebsiella Pneumoniae for high-level production of 3-hydroxypropionic acid.

作者信息

Cao Qing-Yi, Xu Hui-Ying, Ye Bang-Ce, Zhou Ying

机构信息

Laboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China.

出版信息

Arch Microbiol. 2025 Jul 15;207(9):196. doi: 10.1007/s00203-025-04395-z.

DOI:10.1007/s00203-025-04395-z
PMID:40663134
Abstract
摘要

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本文引用的文献

1
Expanding the genetic toolkit of Yarrowia lipolytica: Dynamic promoter engineering enables high-titer biosynthesis of 3-hydroxypropionic acid.扩展解脂耶氏酵母的基因工具包:动态启动子工程实现3-羟基丙酸的高滴度生物合成。
Bioresour Technol. 2025 Sep;432:132656. doi: 10.1016/j.biortech.2025.132656. Epub 2025 May 10.
2
Metabolic Remodulation of Chassis and Corn Stover Bioprocessing to Unlock 3-Hydroxypropionic Acid Biosynthesis from Agrowaste-Derived Substrates.底盘和玉米秸秆生物加工的代谢重排,以从农业废弃物衍生的基质中解锁 3-羟基丙酸的生物合成。
J Agric Food Chem. 2024 Feb 7;72(5):2536-2546. doi: 10.1021/acs.jafc.3c08419. Epub 2024 Jan 23.
3
Efficient biosynthesis of 3-hydroxypropionic acid from glucose through multidimensional engineering of Escherichia coli.
通过大肠杆菌的多维工程化从葡萄糖高效生物合成 3-羟基丙酸。
Bioresour Technol. 2023 Dec;389:129822. doi: 10.1016/j.biortech.2023.129822. Epub 2023 Oct 5.
4
Comprehensive Genomic Analysis Reveals Extensive Diversity of Type I and Type IV Secretion Systems in Klebsiella pneumoniae.全面基因组分析揭示肺炎克雷伯氏菌中 I 型和 IV 型分泌系统的广泛多样性。
Curr Microbiol. 2023 Jul 5;80(8):270. doi: 10.1007/s00284-023-03362-5.
5
Biosynthesis pathways and strategies for improving 3-hydroxypropionic acid production in bacteria.细菌中 3-羟基丙酸生产的生物合成途径和策略。
World J Microbiol Biotechnol. 2021 Jun 15;37(7):117. doi: 10.1007/s11274-021-03091-6.
6
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis.蓝色盐单胞菌的 3-羟基丙酸的过度生产。
Nat Commun. 2021 Mar 8;12(1):1513. doi: 10.1038/s41467-021-21632-3.
7
Development of Klebsiella pneumoniae J2B as microbial cell factory for the production of 1,3-propanediol from glucose.从葡萄糖生产 1,3-丙二醇的工程菌 Klebsiella pneumoniae J2B 的构建。
Metab Eng. 2020 Nov;62:116-125. doi: 10.1016/j.ymben.2020.09.001. Epub 2020 Sep 6.
8
High-level production of 3-hydroxypropionic acid from glycerol as a sole carbon source using metabolically engineered Escherichia coli.利用代谢工程化的大肠杆菌(Escherichia coli)以甘油为唯一碳源高效生产 3-羟基丙酸。
Biotechnol Bioeng. 2020 Jul;117(7):2139-2152. doi: 10.1002/bit.27344. Epub 2020 Apr 8.
9
-A Useful Pathogenic Strain for Biotechnological Purposes: Diols Biosynthesis under Controlled and Uncontrolled pH Levels.- 一种用于生物技术目的的有用致病菌株:在可控和不可控pH水平下的二醇生物合成。
Pathogens. 2019 Dec 11;8(4):293. doi: 10.3390/pathogens8040293.
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Appl Microbiol Biotechnol. 2019 May;103(10):4017-4031. doi: 10.1007/s00253-019-09772-5. Epub 2019 Mar 29.