Muhetaer Kadeliya, Abulimiti Tangnuer, Abuduxikuer Guzhanuer, Abudurexiti Guligeina, Zhuo Qian, Li Wenyun, Ouyang Yumei, Wen Xuelian, Reheman Maihebubai, Aizezi Anaerguli, Song Shuming, Tuerxun Gulixian, Rezhake Remila, Abulizi Guzhalinuer
Gynecological Oncology Center, Affiliated Cancer Hospital of Xinjiang Medical University, 789 Suzhou East Street, Xinshiqu District, Urumqi, 830000, China.
Xinjiang Key Laboratory of Oncology, Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, 830000, China.
Sci Rep. 2025 Jul 15;15(1):25515. doi: 10.1038/s41598-025-11291-5.
To investigate the awareness, willingness, and barriers to Human Papillomavirus (HPV) vaccine among women in regions with relatively insufficient medical resources. A screening population of women aged 25-83 from Bachu and Moyu counties in China received a structured interview questionnaire survey from February 2023 to August 2024. A total of 8,618 individuals participated in the survey. Only 30.0% and 35.4% were aware of HPV and the HPV vaccine, respectively. Residing in Bachu, having education, non-agricultural occupations, and a history of cervical lesions or inflammation were associated with higher awareness of HPV and its vaccine. The awareness scores showed a downward trend among women aged 35 and older (p < 0.05). Notably, only 1.1% had received the vaccine, while 91.3% expressed a willingness to receive it for themselves and 85.3% for their daughters. The main reasons for refusal were the perception of no risk or daughters being too young. Factors such as work status, recent screening, and awareness increased self-vaccination intention while being single demonstrated a negative impact on these intentions (OR = 0.79, 95% CI: 0.65-0.97). A weak linear association between awareness scores and vaccination willingness while a relatively stronger correlation was identified between one's own vaccination willingness and the willingness to vaccinate their daughters (τ_b = 0.36, p < 0.05). Enhancing awareness and vaccine acceptance among elderly illiterate rural women not only relies on education but also the early screening, diagnosis, and treatment of cervical lesions.
调查医疗资源相对匮乏地区女性对人乳头瘤病毒（HPV）疫苗的认知、接种意愿及障碍。2023年2月至2024年8月，对来自中国巴楚县和墨玉县的25至83岁女性筛查人群进行了结构化访谈问卷调查。共有8618人参与调查。分别仅有30.0%和35.4%的人知晓HPV及HPV疫苗。居住在巴楚、受过教育、从事非农业职业以及有宫颈病变或炎症史与对HPV及其疫苗的较高认知相关。35岁及以上女性的认知得分呈下降趋势（p < 0.05）。值得注意的是，仅1.1%的人接种过疫苗，而91.3%表示自己愿意接种，85.3%表示愿意为女儿接种。拒绝接种的主要原因是认为无风险或女儿年龄太小。工作状态、近期筛查和认知等因素增加了自我接种意愿，而单身则对这些意愿有负面影响（比值比=0.79，95%置信区间：0.65-0.97）。认知得分与接种意愿之间存在微弱的线性关联，而自身接种意愿与为女儿接种意愿之间的相关性相对较强（τ_b = 0.36，p < 0.05）。提高老年农村文盲女性的认知和疫苗接受度不仅依赖于教育，还依赖于宫颈病变的早期筛查、诊断和治疗。
