Pradhan Eli, Gurung Rachni, Shrestha Sadichhya, Wagle Bivek, Duwal Sushma, Paudel Jyoti Bastola, Sharma Sanjita, Shrestha Smita, Thapa Raba, Manandhar Anu, Poudel Manish
Tilganga Institute of Ophthalmology, Gaushala, Nepal.
The Ohio State University, Columbus, OH, USA.
BMC Ophthalmol. 2025 Jul 15;25(1):409. doi: 10.1186/s12886-025-04215-4.
Clinically, the dengue virus can cause hemorrhagic complications or ocular inflammation. This virus can cause anterior uveitis to panuveitis. During acute phase, subconjunctival hemorrhage is a relatively common finding. Dengue associated maculopathy is one of the most common posterior segment findings that include both retinal hemorrhages, cotton wool spots, and macular edema.
To identify clinical features and visual outcome of dengue related retinopathy in patients at a tertiary eye hospital.
A retrospective observational case series was conducted at the Tilganga Institute of Ophthalmology, Nepal focusing on all instances of dengue fever associated with retinal complications during the outbreak from August to October 2022.
Thirty-six patients were enrolled in the study, out of them, 18 (50%) were male and 18 (50%) were female. The average age ± SD of the patients was 9.0 ± 17 years (ranged 14 to 76 years). Thirty-five (97.2%) of the patients reported a decrease in vision and among them 25 (71.4%) experienced unilateral vision loss, while 10 (28.6%) exhibited bilateral involvement.
The ocular manifestations of dengue-associated eye disease range from vague symptoms to serious, perhaps blinding ocular involvement. Due to the recent increase in dengue outbreaks and the global spread of the dengue virus, all eye care providers should be aware of the many ocular signs of dengue-associated eye illness.
临床上，登革热病毒可引起出血性并发症或眼部炎症。该病毒可导致从前葡萄膜炎到全葡萄膜炎。在急性期，结膜下出血是相对常见的表现。登革热相关性黄斑病变是最常见的后段表现之一，包括视网膜出血、棉絮斑和黄斑水肿。
确定一家三级眼科医院中登革热相关性视网膜病变患者的临床特征和视力预后。
在尼泊尔蒂尔甘加眼科研究所进行了一项回顾性观察病例系列研究，重点关注2022年8月至10月疫情期间所有与视网膜并发症相关的登革热病例。
36名患者纳入研究，其中18名（50%）为男性，18名（50%）为女性。患者的平均年龄±标准差为9.0±17岁（范围为14至76岁）。35名（97.2%）患者报告视力下降，其中25名（71.4%）出现单眼视力丧失，10名（28.6%）表现为双眼受累。
登革热相关性眼病的眼部表现从模糊症状到严重的、可能导致失明的眼部受累不等。由于近期登革热疫情增加以及登革热病毒的全球传播，所有眼科护理人员都应了解登革热相关性眼病的多种眼部体征。
