Maciel Camila Guadeluppe, Arashiro Priscilla, da Silva Lívia Alves, do Nascimento Ana Isabel, Dos Santos Conrado Danilo, Koch Gabriel Serrano Ramires, da Cunha João Cesar Pereira, Osório Laysa Gomes, Arakaki Letícia Suemi, Mareto Lisany Krug, Rodrigues Maria Eduarda de Souza, de Azevedo Micael Viana, E Silva Robson França Gomes, Pucci Rodrigo Mayer, Pires Samara Tessari, Borges Sara Raquel Pinto, Drumond Simony Portela do Carmo, de Medeiros Márcio José, Ajalla Maria Elizabeth Araújo, Santos-Pinto Cláudia Du Bocage, de Oliveira Everton Falcão
Secretaria Municipal de Saúde Pública de Campo Grande, Campo Grande, MS, Brasil.
Programa de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
BMC Res Notes. 2025 Jul 16;18(1):301. doi: 10.1186/s13104-025-07368-z.
Studies focusing on individuals living with HIV and mental disorders are crucial to inform and enhance care for this inherently vulnerable population group, especially considering that people living with HIV/AIDS (PLHIV) are more likely to develop mental disorders compared to the general population, contributing to lower adherence to antiretroviral therapy (ART). This study cross-sectional study aimed to assess self-reported adherence to antiretroviral therapy among PLHIV and moderate or severe mental disorders in Campo Grande, Mato Grosso do Sul, Brazil. Patient-reported data from PLHIV who received care in at least one of the Psychosocial Care Network facilities of the Brazilian Unified Health System from 2014 to 2018 were collected to assess the adherence to ART. Among the 76 participants eligible, 35 were included in the study. Substance use-related mental disorders were the most prevalent (45.7%), followed by mood disorders (25.7%) and anxiety (11.4%). Most of the participants had a low ART adherence (62.9%), followed by insufficient adherence (22.9%) and good adherence (14.3%). No significant associations were found between the adherence to ART and the study variables. Our findings suggest the importance of assessing adherence based on both direct and indirect measures, as biological markers and self-report.
针对感染艾滋病毒且患有精神障碍的个体开展研究，对于为这一本质上脆弱的人群提供信息并改善护理至关重要，特别是考虑到与普通人群相比，艾滋病毒/艾滋病感染者更易患精神障碍，这会导致对抗逆转录病毒疗法（ART）的依从性降低。本横断面研究旨在评估巴西南马托格罗索州大坎普市艾滋病毒/艾滋病感染者对抗逆转录病毒疗法的自我报告依从性以及中度或重度精神障碍情况。收集了2014年至2018年期间在巴西统一卫生系统心理社会护理网络设施中至少接受过一次护理的艾滋病毒/艾滋病感染者的患者报告数据，以评估其对抗逆转录病毒疗法的依从性。在76名符合条件的参与者中，35名被纳入研究。与物质使用相关的精神障碍最为普遍（45.7%），其次是情绪障碍（25.7%）和焦虑症（11.4%）。大多数参与者对抗逆转录病毒疗法的依从性较低（62.9%），其次是依从性不足（22.9%）和依从性良好（14.3%）。在对抗逆转录病毒疗法的依从性与研究变量之间未发现显著关联。我们的研究结果表明，基于直接和间接测量方法（如生物学标志物和自我报告）评估依从性具有重要意义。
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