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社会支持和 HIV 污名对抑郁与泰国男男性行为者抗逆转录病毒治疗药物依从性关联的调节作用

The Moderating Role of Social Support and HIV Stigma on the Association Between Depression and ART Adherence Among Young Thai Men Who Have Sex with Men.

机构信息

Department of Psychology, San Diego State University, San Diego, CA, USA.

Center of Excellence in Research on Gender, Sexuality and Health, Faculty of Social Sciences and Humanities, Mahidol University, Nakhon Pathom, Thailand.

出版信息

AIDS Behav. 2023 Sep;27(9):2959-2968. doi: 10.1007/s10461-023-04018-y. Epub 2023 Mar 31.

DOI:10.1007/s10461-023-04018-y
PMID:37000384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10524997/
Abstract

In Thailand, antiretroviral therapy (ART) programs still have difficulties reaching and promoting adherence among a key population - young men who have sex with men (YMSM) living with HIV. As such, we sought to examine potential psychosocial barriers that may contribute to suboptimal levels of ART adherence for this population. Data were drawn from a study of 214 YMSM living with HIV from Bangkok, Thailand. Linear regression models tested the association between depression and ART adherence, and whether social support and HIV-related stigma moderated that relationship. Multivariable models demonstrated social support was significantly associated with higher levels of ART adherence, and that there was a three-way interaction between depression, social support, and HIV-related stigma on ART adherence. These results further our understanding of the role of depression, stigma, and social support in ART adherence among Thai YMSM living with HIV, and that additional supports for YMSM with depression and HIV-related stigma are needed.

摘要

在泰国，抗逆转录病毒疗法（ART）项目仍然难以接触和促进关键人群——感染艾滋病毒的男男性行为者（MSM）的依从性。因此，我们试图研究可能导致该人群 ART 依从性不理想的潜在心理社会障碍。数据来自于对来自泰国曼谷的 214 名感染艾滋病毒的男男性行为者的研究。线性回归模型检验了抑郁与 ART 依从性之间的关系，以及社会支持和与 HIV 相关的耻辱感是否调节了这种关系。多变量模型表明，社会支持与更高水平的 ART 依从性显著相关，抑郁、社会支持和与 HIV 相关的耻辱感之间存在三向相互作用，影响 ART 依从性。这些结果进一步了解了抑郁、耻辱感和社会支持在泰国 HIV 感染 MSM 中对 ART 依从性的作用，需要为有抑郁和与 HIV 相关耻辱感的 MSM 提供更多支持。

相似文献

[1]
The Moderating Role of Social Support and HIV Stigma on the Association Between Depression and ART Adherence Among Young Thai Men Who Have Sex with Men.

AIDS Behav. 2023-9

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[7]
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[2]
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[3]
Effects of intimate partner violence and homophobic bullying on ART adherence among young Thai men who have sex with men: a causal mediation analysis.

BMC Public Health. 2025-3-25

[4]
A Syndemic Clustering of Adversities on Suicide Risk among YMSM Living with HIV in Bangkok: A Causal Latent Class Analysis.

AIDS Behav. 2025-2

[5]
Childhood Sexual Trauma, Substance Use, and Antiretroviral Therapy Adherence Among Older Adults Living With HIV: A Mediational Analysis.

J Appl Gerontol. 2025-2

[6]
Internalized HIV stigma and viral suppression: examining the mediating and moderating roles of substance use and social support.

AIDS. 2024-12-1

[7]
Application progress of latent class growth models in dynamic prevention and control strategies for acquired immunodeficiency syndrome.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024-4-28

[8]
Interaction of social support and depressive symptoms on antiretroviral therapy adherence among people living with HIV in South Africa.

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[9]
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Eur J Investig Health Psychol Educ. 2024-4-19

[10]
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J Int Assoc Provid AIDS Care. 2024

本文引用的文献

[1]
"Kids these days pretend to be grownups" (dekkaedaet): sexual control and negotiation among young Thai female students.

BMC Public Health. 2021-5-1

[2]
Integration and scale-up of efforts to measure and reduce HIV-related stigma: the experience of Thailand.

AIDS. 2020-9-1

[3]
The prevalence of depression in men who have sex with men (MSM) living with HIV: A meta-analysis of comparative and epidemiological studies.

Gen Hosp Psychiatry. 2020

[4]
Validation of a brief version of the Social Provisions Scale using Canadian national survey data.

Health Promot Chronic Dis Prev Can. 2019-12

[5]
Changes in ART Adherence Relate to Changes in depression as Well! Evidence for the Bi-directional Longitudinal Relationship Between Depression and ART Adherence from a Prospective Study of HIV Clients in Uganda.

AIDS Behav. 2020-6

[6]
Revisiting the 'Thai gay paradise': Negative attitudes toward same-sex relations despite sexuality education among Thai LGBT students.

Glob Public Health. 2020-3

[7]
Leveraging early HIV diagnosis and treatment in Thailand to conduct HIV cure research.

AIDS Res Ther. 2019-9-6

[8]
Getting by with a Little Help from Our Friends: The Role of Social Support in Addressing HIV-related Mental Health Disparities among Sexual Minorities in the Lower Rio Grande Valley.

J Homosex. 2021-1-28

[9]
Psychological correlates and binge drinking behaviours among Canadian youth: a cross-sectional analysis of the mental health pilot data from the COMPASS study.

BMJ Open. 2019-6-29

[10]
HIV microaggressions: a novel measure of stigma-related experiences among people living with HIV.

J Behav Med. 2020-2

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