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一例以晕厥和神经功能缺损而非疼痛为表现的斯坦福A型主动脉夹层:诊断陷阱与治疗困境

A Case of Stanford Type A Aortic Dissection Presenting as Syncope and Neurologic Deficits Without Pain: Diagnostic Pitfalls and a Therapeutic Dilemma.

作者信息

Ismail Umar

机构信息

Medicine, NHS Wales, Wales, GBR.

出版信息

Cureus. 2025 Jul 15;17(7):e87979. doi: 10.7759/cureus.87979. eCollection 2025 Jul.

DOI:10.7759/cureus.87979
PMID:40666265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12261810/
Abstract

Acute aortic dissection (AAD) is a true medical emergency that classically presents with sudden severe tearing chest pain that may radiate to the back or with tearing abdominal pain. When it presents atypically without pain, diagnostic delays or misdiagnosis are common, often with devastating consequences. We report the case of a 59-year-old male with uncontrolled hypertension who first presented to an outside emergency department (ED) with multiple collapses and was discharged after assessment. He presented 48 hours later to our ED following collapse and loss of consciousness. The patient was in shock upon arrival. Transient right upper limb weakness and slurring of speech were noted on initial assessment. Acute coronary syndrome (ACS) with cardiogenic shock was suspected on the basis of electrocardiographic (ECG) changes and raised troponin, and ACS treatment was administered. However, bedside echocardiogram performed to assess left ventricular function as part of the ACS work-up suggested Stanford type A AAD, which was confirmed by computed tomogram (CT) of the aorta. Emergency surgical repair of the aorta was performed after transfer to a tertiary hospital, with good postoperative recovery. This case highlights the importance of maintaining a high index of suspicion for aortic dissection in patients presenting with syncope and neurological deficits even in the absence of classical symptoms. Simulation training specifically tailored to scenarios of atypical presentations of AAD may be of benefit to emergency clinicians and help reduce the unacceptably high rate of misdiagnosis.

摘要

急性主动脉夹层(AAD)是一种真正的医疗急症,典型表现为突发的严重撕裂样胸痛,可放射至背部,或伴有撕裂样腹痛。当表现不典型且无疼痛时,诊断延迟或误诊很常见,往往会带来灾难性后果。我们报告一例59岁男性病例,该患者患有未控制的高血压,最初因多次晕倒被送至外院急诊科,评估后出院。48小时后,他在再次晕倒和意识丧失后被送至我院急诊科。患者入院时处于休克状态。初始评估时发现有短暂性右上肢无力和言语不清。基于心电图(ECG)变化和肌钙蛋白升高,怀疑为急性冠状动脉综合征(ACS)并伴有心源性休克,遂给予ACS治疗。然而,作为ACS检查一部分而进行的床边超声心动图检查提示为斯坦福A型AAD,主动脉计算机断层扫描(CT)证实了这一诊断。转至三级医院后进行了紧急主动脉手术修复,术后恢复良好。该病例强调,即使没有典型症状,对于出现晕厥和神经功能缺损的患者,保持对主动脉夹层的高度怀疑指数非常重要。专门针对AAD非典型表现场景进行的模拟培训可能对急诊临床医生有益,并有助于降低高得令人无法接受的误诊率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/7b4eaef554be/cureus-0017-00000087979-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/30a2d1d8e306/cureus-0017-00000087979-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/7877cb02226f/cureus-0017-00000087979-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/1d0f677aec1b/cureus-0017-00000087979-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/01641bf85c94/cureus-0017-00000087979-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/7b4eaef554be/cureus-0017-00000087979-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/30a2d1d8e306/cureus-0017-00000087979-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/7877cb02226f/cureus-0017-00000087979-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/1d0f677aec1b/cureus-0017-00000087979-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/01641bf85c94/cureus-0017-00000087979-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/539c/12261810/7b4eaef554be/cureus-0017-00000087979-i05.jpg

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