Niyibizi Jean Berchmans, Okop Kufre Joseph, Levitt Naomi, Rulisa Stephen, Ntawuyirushintege Seleman, Tumusiime David, Nyandwi Alypio, Ntaganda Evariste, Ayele Birhanu, Bavuma Charlotte
Single Project Implementation Unit, University of Rwanda, Kicukiro, Kigali, Rwanda.
Chronic Diseases Initiative for Africa (CDIA), University of Cape Town, Rondebosch, Western Cape, South Africa.
Rwanda J Med Health Sci. 2021 Apr 8;4(1):166-184. doi: 10.4314/rjmhs.v4i1.12. eCollection 2021 Apr.
In Rwanda, cardiovascular diseases (CVDs) ranked second of the most common cause of death in 2016. CVD risk score tools have been recommended to identify people at high risk for management.
To assess the comparability of body mass index (BMI)-based and lipid-based CVD risk scores in Rwandan population.
Secondary analysis was conducted on 4185 study participants extracted from the dataset of Rwanda 2012-2013 non-communicable diseases risk factors survey. Individual CVD risk scores were calculated using both BMI-based and lipid-based algorithms, one at a time. Spearman rank's coefficient and Cohen's Kappa coefficient were used to compare the two tools.
About 63.5% of participants were women. There was a significant positive correlation between BMI-based algorithm and lipid-based algorithm vis-à-vis a 10-year CVD risk prediction (Spearman rank correlation coefficients > 0.90, p<0.001) considering either men, women or overall study participants. There was a moderate agreement between BMI-based and lipid-based algorithms vis-à-vis CVD risk characterization, kappa = 0.52; p-value p<0.001 considering either overall study participants or men and kappa = 0.48; p-value p<0.001 considering women.
The findings from this study suggest the use of BMI-based algorithm, a cost effective tool compared to lipid-based tool, can be alternatively used in resource-limited settings.
在卢旺达,心血管疾病(CVDs)在2016年是第二大常见死因。已推荐使用心血管疾病风险评分工具来识别高危人群以便进行管理。
评估基于体重指数(BMI)和基于血脂的心血管疾病风险评分在卢旺达人群中的可比性。
对从2012 - 2013年卢旺达非传染性疾病危险因素调查数据集提取的4185名研究参与者进行二次分析。分别使用基于BMI和基于血脂的算法依次计算个体心血管疾病风险评分。采用Spearman秩相关系数和Cohen's Kappa系数来比较这两种工具。
约63.5%的参与者为女性。考虑男性、女性或全体研究参与者时,基于BMI的算法和基于血脂的算法在预测10年心血管疾病风险方面存在显著正相关(Spearman秩相关系数>0.90,p<0.001)。基于BMI的算法和基于血脂的算法在心血管疾病风险特征方面存在中度一致性,总体研究参与者或男性的kappa = 0.52;p值p<0.001,女性的kappa = 0.48;p值p<0.001。
本研究结果表明,与基于血脂的工具相比,基于BMI的算法是一种经济有效的工具,在资源有限的环境中可替代使用。