Tamiya N, Yagi T
J Biochem. 1985 Aug;98(2):289-303. doi: 10.1093/oxfordjournals.jbchem.a135282.
A "non-divergence theory" is proposed for the mechanism of evolution. The theory is based on the observation that comparison of the amino acid sequences of related proteins in various organisms gives inconsistent results from one type of protein to another, and on the occurrence of significant gene transfer among living organisms. Special attention is focused on the sequence comparisons of short- and long-chain neurotoxins and phospholipases A2 from the venoms of proteroglyphous snakes and those of microbial ferredoxins, rubredoxins, and flavodoxins.
针对进化机制提出了一种“非分歧理论”。该理论基于以下观察结果:对各种生物体中相关蛋白质的氨基酸序列进行比较,从一种蛋白质类型到另一种蛋白质类型会得出不一致的结果,以及生物体之间存在显著的基因转移。特别关注前沟牙毒蛇毒液中的短链和长链神经毒素以及磷脂酶A2与微生物铁氧化还原蛋白、红素氧化还原蛋白和黄素氧化还原蛋白的序列比较。