Kalogeropoulos Dimitrios, Ibraheem Ahmed, Dragnev Daniel
Ophthalmology, St Helens Hospital, Mersey and West Lancashire Teaching Hospitals NHS Trust, St Helens, GBR.
Cureus. 2025 Jun 15;17(6):e86048. doi: 10.7759/cureus.86048. eCollection 2025 Jun.
Retinal pigment epithelial detachments (PEDs) result from a disruption at the junction between the basement membrane of the retinal pigment epithelium (RPE) and the innermost part of Bruch's membrane. Serous retinal PEDs, whether singular or multiple, are frequently seen across a broad spectrum of ophthalmic disorders. Additionally, PEDs have been associated with various systemic conditions, including renal, hypertensive, endocrine, and hematologic disorders. Idiopathic PEDs, which occur without an associated underlying condition, are exceedingly rare, with only a few cases reported in the literature. Herein, we report a case of an asymptomatic and otherwise healthy individual with multiple idiopathic retinal PEDs, highlighting the importance of a comprehensive clinical examination and multimodal ophthalmic imaging.
视网膜色素上皮脱离(PEDs)是由视网膜色素上皮(RPE)基底膜与布鲁赫膜最内层之间的连接处破坏引起的。浆液性视网膜PEDs,无论是单发还是多发,在广泛的眼科疾病中都很常见。此外,PEDs还与各种全身性疾病有关,包括肾脏、高血压、内分泌和血液系统疾病。特发性PEDs在没有相关基础疾病的情况下发生,极为罕见,文献中仅报道了少数病例。在此,我们报告一例无症状且其他方面健康的个体患有多发特发性视网膜PEDs的病例,强调了全面临床检查和多模式眼科成像的重要性。