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经导管主动脉瓣植入术(TAVI)能否在没有现场心脏外科手术的情况下进行?

Can TAVI be performed without on-site cardiac surgery?

作者信息

Lodo V, Barbero C, Salizzoni S, Zingarelli E, Torre M La, Enrico Italiano G, Centofanti P, Rinaldi M

机构信息

Department of Cardiac Surgery, Azienda Ospedaliera Ordine Mauriziano, Turin, Italy.

Cardiac Surgery, Città della Salute e della Scienza Hospital, Turin, Italy.

出版信息

Int J Cardiol Heart Vasc. 2025 Jul 7;59:101736. doi: 10.1016/j.ijcha.2025.101736. eCollection 2025 Aug.

Abstract

INTRODUCTION

Aim of this analysis in to assess the prevalence and post-procedural outcomes of surgical bailout during transcatheter aortic valve implantation (TAVI).

METHODS

Patients undergoing TAVI from September 2017 to March 2023 were enrolled from two high volume centers. All the procedures were performed with on-site cardiac surgery, but especially the scrubbed cardiac surgeon. The primary endpoint was in-hospital mortality of TAVI patients after emergent cardiac surgery (ECS). Secondary endpoints were intra-operative and 1-year mortality, and post-procedural complications such as acute kidney injury (AKI), stroke, myocardial infarction (MI), conduction abnormalities, need for inotropic support and intensive care unit (ICU) and in- hospital length of stay.

RESULTS

A total of 1347 consecutive patients underwent transfemoral TAVI. Ten patients (0.74 %), representing the study population, reported intra-procedural complications requiring ECS: seven patients received a self-expandable prosthesis; three patients received a balloon expandable prosthesis. Indications for ECS included: type A dissection (n = 2), aortic annulus rupture (n = 1), left(n = 1) and right (n = 2) ventricle perforation, mitral valve apparatus damage (n = 2), prosthesis embolization (n = 2). Four patients required post-operative inotropic support. One case of minor stroke and one case of AKI (grade III) were reported. Three patients developed a post procedural left bundle branch block (LBBB). Median ICU and hospital length-of-stay were 4.5 (2-7.75) days and 14 (8-22) days, respectively. One case of in-hospital mortality was reported.

CONCLUSIONS

The on-site cardiac surgery, with the scrubbed heart surgeon, represents a life-saving resource for TAVI centers in case of ECS, and it is essential to achieve low-rate in-hospital mortality.

摘要

引言

本分析的目的是评估经导管主动脉瓣植入术(TAVI)期间外科紧急救援的发生率和术后结果。

方法

2017年9月至2023年3月接受TAVI的患者来自两个高容量中心。所有手术均在现场心脏外科医生,尤其是经过严格筛选的心脏外科医生的参与下进行。主要终点是紧急心脏手术后(ECS)TAVI患者的住院死亡率。次要终点是术中及1年死亡率,以及术后并发症,如急性肾损伤(AKI)、中风、心肌梗死(MI)、传导异常、是否需要使用血管活性药物支持以及重症监护病房(ICU)治疗和住院时间。

结果

共有1347例连续患者接受了经股动脉TAVI。10例患者(0.74%),即研究人群,报告了术中需要ECS的并发症:7例患者接受了自膨胀式假体;3例患者接受了球囊扩张式假体。ECS的指征包括:A型夹层(n = 2)、主动脉瓣环破裂(n = 1)、左心室(n = 1)和右心室穿孔(n = 2)、二尖瓣装置损伤(n = 2)、假体栓塞(n = 2)。4例患者术后需要血管活性药物支持。报告了1例轻度中风和1例AKI(III级)。3例患者术后出现左束支传导阻滞(LBBB)。ICU和住院时间的中位数分别为4.5(2 - 7.75)天和14(8 - 22)天。报告了1例住院死亡病例。

结论

对于TAVI中心而言,现场心脏外科医生,尤其是经过严格筛选的心脏外科医生,在ECS情况下是一种挽救生命的资源,对于实现低住院死亡率至关重要。

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