• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

前交叉韧带重建术后静脉血栓栓塞症的预防:回顾性病例对照研究。

Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study.

作者信息

Afana Hatem B, Ashokan Shine, Nau Thomas

机构信息

Orthopaedic Department, King's College Hospital London Dubai, Dubai Hills, Alkhail Road, Marabea' East Exit, PO Box No 340901, Dubai, United Arab Emirates.

Orthopaedic Department, King's College Hospital London Dubai, Dubai Hills, Alkhail Road, Marabea' East Exit, PO Box No 340901, Dubai, United Arab Emirates - Mohammed Bin Rashid University of Medicine and Health Sciences, Building 14, Dubai Healthcare City, PO Box 505055, Dubai United Arab Emirates.

出版信息

SICOT J. 2025;11:38. doi: 10.1051/sicotj/2025032. Epub 2025 Jul 16.

DOI:10.1051/sicotj/2025032
PMID:40668978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12266665/
Abstract

INTRODUCTION

Venous thromboembolism (VTE) is a rare but potentially serious complication following anterior cruciate ligament reconstruction (ACLR). There is no guideline for the routine use of anticoagulants post-ACLR surgery.

METHODS

This retrospective case-control study reviewed 199 patients who underwent ACLR between February 2020 and November 2024. Two groups were compared: Group A (n = 113) received no pharmacological prophylaxis, while Group B (n = 86) received low-molecular-weight heparin (LMWH) for 2 weeks postoperatively. The incidence of symptomatic VTE, postoperative bleeding, and related complications was evaluated.

RESULTS

No symptomatic VTE or bleeding complications were observed in either group. There was no statistically significant difference between the groups in terms of age, BMI, smoking, comorbidities, and postoperative weight bearing. There was a significant difference in surgical duration, graft type, and meniscal procedure.

DISCUSSION

Our findings support a risk-stratified approach rather than universal pharmacologic prophylaxis in ACLR patients.

摘要

引言

静脉血栓栓塞症(VTE)是前交叉韧带重建术(ACLR)后一种罕见但可能严重的并发症。目前尚无ACLR术后常规使用抗凝剂的指南。

方法

这项回顾性病例对照研究纳入了2020年2月至2024年11月期间接受ACLR的199例患者。比较了两组:A组(n = 113)未接受药物预防,而B组(n = 86)术后接受低分子量肝素(LMWH)治疗2周。评估了有症状VTE、术后出血及相关并发症的发生率。

结果

两组均未观察到有症状的VTE或出血并发症。两组在年龄、体重指数、吸烟、合并症及术后负重方面无统计学显著差异。手术时间、移植物类型和半月板手术存在显著差异。

讨论

我们的研究结果支持对ACLR患者采用风险分层方法,而非普遍进行药物预防。

相似文献

1
Venous thromboembolism prophylaxis after anterior cruciate ligament reconstruction: retrospective case-control study.前交叉韧带重建术后静脉血栓栓塞症的预防:回顾性病例对照研究。
SICOT J. 2025;11:38. doi: 10.1051/sicotj/2025032. Epub 2025 Jul 16.
2
Interventions for preventing venous thromboembolism in adults undergoing knee arthroscopy.成人膝关节镜检查中预防静脉血栓栓塞症的干预措施。
Cochrane Database Syst Rev. 2022 Aug 22;8(8):CD005259. doi: 10.1002/14651858.CD005259.pub5.
3
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy.接受化疗的门诊癌症患者静脉血栓栓塞的一级预防
Cochrane Database Syst Rev. 2016 Dec 1;12(12):CD008500. doi: 10.1002/14651858.CD008500.pub4.
4
Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair.延长疗程的抗凝剂用于预防全髋关节或膝关节置换术后或髋部骨折修复后的静脉血栓栓塞。
Cochrane Database Syst Rev. 2016 Mar 30;3(3):CD004179. doi: 10.1002/14651858.CD004179.pub2.
5
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery.药物干预预防接受减重手术人群的静脉血栓栓塞症。
Cochrane Database Syst Rev. 2022 Nov 22;11(11):CD013683. doi: 10.1002/14651858.CD013683.pub2.
6
Surgical versus conservative interventions for treating anterior cruciate ligament injuries.治疗前交叉韧带损伤的手术与保守干预措施
Cochrane Database Syst Rev. 2016 Apr 3;4(4):CD011166. doi: 10.1002/14651858.CD011166.pub2.
7
Subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism.皮下注射普通肝素用于静脉血栓栓塞症的初始治疗。
Cochrane Database Syst Rev. 2017 Feb 14;2(2):CD006771. doi: 10.1002/14651858.CD006771.pub3.
8
Pentasaccharides for the prevention of venous thromboembolism.用于预防静脉血栓栓塞的五糖
Cochrane Database Syst Rev. 2016 Oct 31;10(10):CD005134. doi: 10.1002/14651858.CD005134.pub3.
9
Interventions for implementation of thromboprophylaxis in hospitalized patients at risk for venous thromboembolism.对有静脉血栓栓塞风险的住院患者实施血栓预防的干预措施。
Cochrane Database Syst Rev. 2018 Apr 24;4(4):CD008201. doi: 10.1002/14651858.CD008201.pub3.
10
Direct factor Xa inhibitors versus low molecular weight heparins or vitamin K antagonists for prevention of venous thromboembolism in elective primary hip or knee replacement or hip fracture repair.在择期初次髋关节或膝关节置换术或髋部骨折修复中,直接凝血因子Xa抑制剂与低分子量肝素或维生素K拮抗剂用于预防静脉血栓栓塞的比较
Cochrane Database Syst Rev. 2025 Jan 27;1(1):CD011762. doi: 10.1002/14651858.CD011762.pub2.

本文引用的文献

1
Use of tourniquet in anterior cruciate ligament reconstruction: Is it truly necessary? A prospective randomized clinical trial.使用止血带在前交叉韧带重建术中:真的有必要吗?一项前瞻性随机临床试验。
J Orthop Surg (Hong Kong). 2024 Sep-Dec;32(3):10225536241293538. doi: 10.1177/10225536241293538.
2
Effectiveness of non-instrumental early mobilization to reduce the incidence of deep vein thrombosis in hospitalized patients: A systematic review and meta-analysis.非器械性早期活动对降低住院患者深静脉血栓形成发生率的有效性:一项系统评价和荟萃分析
Int J Nurs Stud. 2025 Jan;161:104917. doi: 10.1016/j.ijnurstu.2024.104917. Epub 2024 Sep 25.
3
Risk factors for venous thromboembolism following knee arthroscopy: A systematic review and meta-analysis of observational studies.膝关节镜检查后静脉血栓栓塞的危险因素:观察性研究的系统评价和荟萃分析
Heliyon. 2024 Feb 10;10(4):e25939. doi: 10.1016/j.heliyon.2024.e25939. eCollection 2024 Feb 29.
4
The efficacy and safety of low-molecular-weight heparin in patients undergoing knee arthroscopic surgery and anterior cruciate ligament reconstruction.低分子量肝素在接受膝关节镜手术和前交叉韧带重建患者中的疗效与安全性。
Heliyon. 2023 Sep 6;9(9):e19696. doi: 10.1016/j.heliyon.2023.e19696. eCollection 2023 Sep.
5
American Academy of Orthopaedic Surgeons Clinical Practice Guideline Summary: Management of Anterior Cruciate Ligament Injuries.美国矫形外科医师学会临床实践指南摘要:前交叉韧带损伤的治疗。
J Am Acad Orthop Surg. 2023 Jun 1;31(11):531-537. doi: 10.5435/JAAOS-D-22-01020. Epub 2023 Jan 18.
6
The incidence of deep vein thrombosis after anterior cruciate ligament reconstruction: An analysis using routine ultrasonography of 260 patients.前交叉韧带重建术后深静脉血栓形成的发生率:260 例患者常规超声分析。
PLoS One. 2022 Dec 14;17(12):e0279136. doi: 10.1371/journal.pone.0279136. eCollection 2022.
7
Anticoagulant Usage After Anterior Cruciate Ligament Reconstruction Is Associated With Increased Rate of Manipulation Under Anesthesia.前交叉韧带重建术后抗凝药物的使用与麻醉下手法复位率增加相关。
J Am Acad Orthop Surg. 2023 Jun 1;31(11):574-580. doi: 10.5435/JAAOS-D-20-01358. Epub 2022 Nov 9.
8
Factors associated with perioperative deep vein thrombosis in arthroscopic anterior cruciate ligament reconstruction.关节镜下前交叉韧带重建围手术期深静脉血栓形成的相关因素。
J Orthop Sci. 2023 Sep;28(5):1041-1045. doi: 10.1016/j.jos.2022.06.003. Epub 2022 Jul 14.
9
Does anterior cruciate ligament reconstruction increase venous thromboembolism risk compared with knee meniscectomy under arthroscopy?与关节镜下膝关节半月板切除术相比,前交叉韧带重建会增加静脉血栓栓塞风险吗?
BMC Musculoskelet Disord. 2022 Mar 18;23(1):268. doi: 10.1186/s12891-022-05216-w.
10
Not Using a Tourniquet May Reduce the Incidence of Asymptomatic Deep Venous Thrombosis After ACL Reconstruction: An Observational Study.不使用止血带可能降低前交叉韧带重建术后无症状性深静脉血栓形成的发生率:一项观察性研究。
Orthop J Sports Med. 2021 Dec 6;9(12):23259671211056677. doi: 10.1177/23259671211056677. eCollection 2021 Dec.