Aminimoghaddam Soheila, Sarchami Niloufar, Mohammadi Marzieh
Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Tehran, Iran.
Int J Surg Case Rep. 2025 Aug;133:111605. doi: 10.1016/j.ijscr.2025.111605. Epub 2025 Jul 3.
Ovarian metastasis from cervical carcinoma (CC) is rare. As adenocarcinomas tend to develop within the endocervix, they may be hidden in Pap tests and have a normal Colposcopic appearance. Only a limited number of Ovarian metastases from CC are reported in the literature, and various aspects of this involvement still need to be clarified.
In this study, we reported a case of unexpected ovarian metastatic cervical cancer in a 57-year-old female. The uniqueness of the present case was the large size of the metastatic ovarian mass, which led to ureter compression from the AC and the good response to chemoradiotherapy. Unlike the previously reported cases in which the ureter was obstructed at the ureter-bladder junction(trigone), in our case, ureter obstruction occurred at the level of the pelvic brim.
Even though ovarian metastasis of cervical cancer is rare, chemoradiotherapy (CRT) manifests a good response with no remnant cervical mass observed in the surgery, which is compatible with the result of a normal Positron emission tomography scan (PET).
Cervical adenocarcinoma can often be diagnosed at very late stages, presenting with large ovarian masses and symptoms of ureter compression. This highlights a lack of awareness regarding appropriate cervical cancer screening tests. Moreover, there is a need for appropriate following imaging methods to differentiate pelvic masses and lymph nodes.
宫颈癌（CC）发生卵巢转移较为罕见。由于腺癌往往发生于宫颈管内，在巴氏涂片检查中可能不易发现，且阴道镜检查外观正常。文献中报道的宫颈癌卵巢转移病例数量有限，这种转移的各个方面仍有待阐明。
在本研究中，我们报告了一例57岁女性意外发生卵巢转移的宫颈癌病例。本病例的独特之处在于转移至卵巢的肿块体积较大，导致输尿管受到肿块压迫，且对放化疗反应良好。与先前报道的输尿管在输尿管膀胱连接处（三角区）受阻的病例不同，在我们的病例中，输尿管梗阻发生在骨盆边缘水平。
尽管宫颈癌卵巢转移罕见，但放化疗（CRT）显示出良好的反应，手术中未观察到残留的宫颈肿块，这与正电子发射断层扫描（PET）结果相符。
宫颈腺癌常常在晚期才被诊断出来，表现为卵巢肿块较大且伴有输尿管受压症状。这凸显了对适当的宫颈癌筛查检查缺乏认识。此外，需要合适的后续影像学方法来鉴别盆腔肿块和淋巴结。
