胰高血糖素样肽-1（GLP-1）药物不断增加的益处。
The expanding benefits of GLP-1 medicines.
作者信息
Gonzalez-Rellan Maria J, Drucker Daniel J
机构信息
Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON M5G1X5, Canada.
Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, ON M5G1X5, Canada.
出版信息
Cell Rep Med. 2025 Jul 15;6(7):102214. doi: 10.1016/j.xcrm.2025.102214.
GLP-1 medicines, initially developed for blood glucose and weight control, improve outcomes in people with cardiovascular, kidney, liver, arthritis, and sleep apnea disorders, actions mediated in part through anti-inflammatory and metabolic pathways, with some benefits partly independent of the degree of weight loss achieved.
最初为控制血糖和体重而研发的胰高血糖素样肽-1（GLP-1）药物，可改善患有心血管、肾脏、肝脏、关节炎和睡眠呼吸暂停症的患者的病情，其作用部分通过抗炎和代谢途径介导，部分益处与体重减轻程度无关。
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