Flodgren Gerd Monika, Chakraverty Digo, Doetsch Julia, Hjertager Krog Norun, Leinsalu Mall, Reile Rainer, Robsahm Trude, Syse Astri, Tammur Kadri, Waldhauer Julia
Norwegian Institute of Public Health, Oslo, Norway
Federal Centre for Health Education, Cologne, Germany.
BMJ Open. 2025 Jul 16;15(7):e900939. doi: 10.1136/bmjopen-2025-900939.
There is evidence for significant inequalities in morbidity and mortality due to cancer and other major non-communicable diseases (NCDs) both within and between European countries. Up-to-date evidence highlighting best practices for future policies is needed to reduce these inequalities.
The objective is to map and summarise published evidence on the impact of national and/or supranational policies on social inequalities in cancer and other NCDs, and their risk factors in Europe, and explore the nature and characteristics of these policies. The criteria for studies to be included are Population: any population group(s), whole population(s) or supranational population in Europe.
any national or supranational policy directly targeting social inequalities in NCDs and/or their risk factors, or NCDs or their risk factors in general, while reporting effects on inequalities or targeting root causes of social inequality.
policies implemented by one or more governments or authorities in the WHO European region, in one or more sectors, and applied in a primordial, primary, secondary or tertiary prevention context. The policies may be universal, targeted or proportionate universal. The review will follow the Johanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping reviews. We will search 13 databases from 2008 up to present for eligible experimental or quasi-experimental studies in any language, and reference lists of relevant reviews and included studies. The databases for the main search will include MEDLINE, Embase, Cochrane CENTRAL, Global Health, American Psychological Association (APA) PsycInfo, Cumulated Index in Nursing and Allied Health Literature (CINAHL), Education Resources Information Center (ERIC), Web of Science Core Collection, Sociological Abstracts, Scopus, EconLit, The Social Interventions Research and Evaluation Network and FRANCIS. Study quality will be assessed using the Effective Practice and Organisation of Care (EPOC) risk of bias tool or the Risk of Bias in Non-Randomised studies of Interventions (ROBINS-I) tool depending on study design. Results will be synthesised narratively using descriptive statistics and visuals.
Ethical approval will not be sought as scoping reviews do not involve primary data collection or direct interaction with human participants. The results of this review, which is part of the JA-PreventNCD project, funded by the European Commission, and involving 25 European countries, will feed into one of the project's deliverables, which comprises recommendations for policymakers based on the best available knowledge. We will also aim to present the results of the review at international conferences and publish the full review in an international peer-reviewed journal.
This protocol is registered on Open Science Framework (https://doi.org/10.17605/OSF.IO/H7MUW).
有证据表明,在欧洲国家内部以及国家之间,癌症和其他主要非传染性疾病(NCDs)导致的发病率和死亡率存在显著不平等现象。需要最新的证据来突出未来政策的最佳实践,以减少这些不平等。
目的是梳理和总结已发表的关于国家和/或超国家政策对欧洲癌症和其他非传染性疾病社会不平等及其风险因素影响的证据,并探讨这些政策的性质和特点。纳入研究的标准为:人群:欧洲的任何人群组、全体人群或超国家人群。
任何直接针对非传染性疾病社会不平等及其风险因素,或一般非传染性疾病及其风险因素的国家或超国家政策,同时报告对不平等的影响或针对社会不平等的根本原因。
世界卫生组织欧洲区域一个或多个政府或当局在一个或多个部门实施的政策,并应用于初级、一级、二级或三级预防背景。这些政策可以是普遍的、有针对性的或适度普遍的。本综述将遵循乔安娜·布里格斯研究所指南以及系统评价和元分析的首选报告项目(PRISMA)扩展版用于范围综述。我们将检索从2008年至今的13个数据库,查找任何语言的合格实验性或准实验性研究,以及相关综述和纳入研究的参考文献列表。主要检索的数据库将包括MEDLINE、Embase、Cochrane CENTRAL、Global Health、美国心理学会(APA)PsycInfo、护理及相关健康文献累积索引(CINAHL)、教育资源信息中心(ERIC)、科学引文索引核心合集、社会学文摘、Scopus、EconLit、社会干预研究与评价网络和FRANCIS。将根据研究设计使用有效护理实践与组织(EPOC)偏倚风险工具或干预非随机研究中的偏倚风险(ROBINS-I)工具评估研究质量。结果将使用描述性统计和可视化进行叙述性综合。
由于范围综述不涉及原始数据收集或与人类参与者的直接互动,因此无需寻求伦理批准。本综述是由欧盟委员会资助、涉及25个欧洲国家的JA-PreventNCD项目的一部分,其结果将纳入该项目的一项可交付成果,即基于现有最佳知识为政策制定者提供建议。我们还旨在在国际会议上展示综述结果,并在国际同行评审期刊上发表完整综述。
本方案已在开放科学框架(https://doi.org/10.17605/OSF.IO/H7MUW)上注册。