Rothschild A J
J Clin Psychopharmacol. 1985 Dec;5(6):340-2.
Two cases of mania following the discontinuation of treatment with isocarboxazid are described. Although this phenomenon has been reported by several investigators to occur after cessation of tricyclic antidepressant therapy, there exists only one isolated report of hypomania after discontinuation of monoamine oxidase inhibitors. Possible mechanisms for the occurrence of hypomania and mania after withdrawal from antidepressants are discussed.
本文描述了两例停用异卡波肼治疗后出现躁狂的病例。尽管有几位研究者报告过这种现象发生在停用三环类抗抑郁药治疗之后,但关于停用单胺氧化酶抑制剂后出现轻躁狂的情况仅有一篇孤立的报告。文中讨论了停用抗抑郁药后出现轻躁狂和躁狂的可能机制。