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使用日本诊断流程组合数据库分析九旬老人颈椎骨折的不良预后因素

Poor Prognostic Factors of Cervical Fracture among Nonagenarians Using the Japanese Diagnosis Procedure Combination Database.

作者信息

Doi Kazuma, Otani Naoki, Inoue Norihiko, Mizuno Junichi, Fushimi Kiyohide, Yoshino Atsuo

机构信息

Department of Neurological Surgery, Nihon University School of Medicine.

Center for Minimally Invasive Spinal Surgery, Shin-Yurigaoka General Hospital.

出版信息

Neurol Med Chir (Tokyo). 2025 Aug 15;65(8):348-354. doi: 10.2176/jns-nmc.2025-0051. Epub 2025 Jul 16.

Abstract

Japan has become a super-aging society compared with other countries, with many healthy super-older people surpassing the average life expectancy. Among this population, there are some patients aged >90 years with cervical fracture. However, few clinical studies have investigated cervical fracture among patients aged >90 years, and its clinical features and outcomes have not been fully elucidated. Therefore, this study aimed to explore the descriptive epidemiology of cervical fracture among patients aged >90 years in Japan using a nationwide database. This retrospective study used the Diagnosis Procedure Combination database, which is a nationwide inpatient database covering more than half of all acute-care hospitals in Japan. A total of 977 patients aged >90 years with a confirmed diagnosis of cervical fracture were included in this study. Data were collected, including medical history, diagnoses, treatments, complications, and outcomes. The results showed that the complication rates among patients aged >90 years with cervical fracture were almost the same as those in previous studies, whereas in-hospital mortality in patients with cervical fracture was higher (15.5%). Furthermore, half of the patients aged >90 years with cervical fracture had polytrauma. Older patients with head and spinal cord injuries and cardiac and respiratory complications were more likely to have a poor prognosis. These findings should be considered when treating patients at high risk regardless of surgery. These novel findings provide valuable insights into cervical fracture in patients aged >90 years based on extensive real-world data from Japan, a country with a rapidly aging population.

摘要

与其他国家相比,日本已成为一个超老龄化社会,有许多健康的超高龄者超过了平均预期寿命。在这一人群中,有一些90岁以上的颈椎骨折患者。然而,很少有临床研究调查90岁以上患者的颈椎骨折情况,其临床特征和预后尚未完全阐明。因此,本研究旨在利用全国性数据库探讨日本90岁以上患者颈椎骨折的描述性流行病学。这项回顾性研究使用了诊断程序组合数据库,该数据库是一个覆盖日本一半以上急性护理医院的全国性住院患者数据库。本研究共纳入977例确诊为颈椎骨折的90岁以上患者。收集了包括病史、诊断、治疗、并发症和预后等数据。结果显示,90岁以上颈椎骨折患者的并发症发生率与以往研究几乎相同,而颈椎骨折患者的院内死亡率较高(15.5%)。此外,90岁以上颈椎骨折患者中有一半患有多发伤。患有头部和脊髓损伤以及心脏和呼吸并发症的老年患者预后较差。在治疗高危患者时,无论是否进行手术,都应考虑这些发现。这些新发现基于日本这个人口快速老龄化国家的大量真实世界数据,为90岁以上患者的颈椎骨折提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3241/12412030/39362d09a12e/1349-8029-65-8-0348-g001.jpg

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