Røe Cecilie, Heide Marte, Søberg Helene L, Brunborg Cathrine, Hoksrud Aasne Fenne, Myhre Kjersti, Brox Jens Ivar, Mørk Marianne
Faculty of Medicine, University of Oslo, Oslo, Norway.
Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway.
J Foot Ankle Res. 2025 Sep;18(3):e70067. doi: 10.1002/jfa2.70067.
Plantar fasciopathy is the most common painful condition in the foot and may imply long-term pain and functional limitations. The purpose of this study was to assess the time pattern of recovery in pain, function, and health-related quality of life over 12 months in patients with plantar fasciopathy and assess whether demographic or clinical characteristics could influence these trajectories.
200 participants referred to specialized care, diagnosed with plantar fasciopathy, and randomly assigned to advice plus customized orthosis or advice plus customized orthosis in combination with radial ESWT, sham-rESWT, or high-load exercises were included. Linear mixed model analysis based on demographic information, clinical characteristics, heel pain during activity and at rest the last week, and functioning and health-related quality at baseline and after 3, 6, and 12 months were conducted.
Pain, function, and health-related quality of life improved gradually from baseline to 12 months follow-up with largest improvement within the first 3 months. Bilateral pain was associated with differential trajectories of pain at rest and foot function over time, and a lack of improvement from 6 to 12 months follow-up.
Different recovery trajectories are important to consider when determining timepoints for follow-up in scientific studies as well as to individualize the clinical follow-up.
ClinicalTrials.gov: NCT03472989.
足底筋膜炎是足部最常见的疼痛病症，可能意味着长期疼痛和功能受限。本研究的目的是评估足底筋膜炎患者在12个月内疼痛、功能及健康相关生活质量的恢复时间模式，并评估人口统计学或临床特征是否会影响这些轨迹。
纳入200名转诊至专科护理、被诊断为足底筋膜炎的参与者，他们被随机分配接受建议加定制矫形器，或建议加定制矫形器联合放射状体外冲击波疗法（rESWT）、假rESWT或高负荷运动。基于人口统计学信息、临床特征、上周活动和休息时的足跟疼痛，以及基线时、3个月、6个月和12个月后的功能及健康相关生活质量进行线性混合模型分析。
从基线到12个月随访期间，疼痛、功能及健康相关生活质量逐渐改善，在最初3个月内改善最大。双侧疼痛与休息时疼痛和足部功能随时间的不同轨迹相关，且在6至12个月随访期间缺乏改善。
在科学研究中确定随访时间点以及使临床随访个体化时，考虑不同的恢复轨迹很重要。
ClinicalTrials.gov：NCT03472989。
