Wang Wenhui, Zhou Ruiyun, Jayan Heera, Yin Limei, Shao Xingjun, Zou Xiaobo, Guo Zhiming
China Light Industry Key Laboratory of Food Intelligent Detection & Processing, School of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Supercritical Extraction Natural Products Engineering Research Center of Jiangsu Province, Jiangsu J.D.Y Bio-tech Co., Ltd, Zhenjiang, China.
Crit Rev Food Sci Nutr. 2025 Jul 17:1-20. doi: 10.1080/10408398.2025.2531224.
Surface-enhanced Raman scattering (SERS) is a fingerprint-type, and nondestructive testing technique that has advantages for testing of hazardous substances in food. However, conventional substrates limit their practical applications due to their high cost, complex preparation, and poor selectivity. Quantum dots (QDs) are emerging as ideal SERS substances, gradually attracting the attention of researchers in the field of sensing. They address the challenges of poor stability and selectivity in SERS technology. The rational design and construction of QDs-SERS substrates are particularly well-suited for detecting hazardous substances in complex food matrices. Despite these advancements, a comprehensive review on the integration of QDs in SERS for food safety applications is still lacking. This review summarizes the recent progress in SERS for detecting food safety hazards, focusing on four key areas: pesticide residues, illegal additives, foodborne pathogens and heavy metal ions. SERS enhancement mechanism and the unique properties of QDs are introduced. The design strategies and application potential of QDs-based SERS substrates in food safety detection are highlighted. Finally, the limitations and future directions of QDs-based SERS substrates in food safety detection are critically discussed.
表面增强拉曼散射（SERS）是一种指纹型无损检测技术，在食品中有害物质检测方面具有优势。然而，传统基底因其成本高、制备复杂且选择性差而限制了其实际应用。量子点（QDs）正成为理想的SERS物质，逐渐吸引传感领域研究人员的关注。它们解决了SERS技术中稳定性和选择性差的挑战。量子点-SERS基底的合理设计与构建特别适合检测复杂食品基质中的有害物质。尽管有这些进展，但仍缺乏关于量子点在用于食品安全应用的SERS中的整合的全面综述。本综述总结了SERS在检测食品安全危害方面的最新进展，重点关注四个关键领域：农药残留、非法添加剂、食源性病原体和重金属离子。介绍了SERS增强机制以及量子点的独特性质。突出了基于量子点的SERS基底在食品安全检测中的设计策略和应用潜力。最后，批判性地讨论了基于量子点的SERS基底在食品安全检测中的局限性和未来方向。
