Wu Zongzhou, Wang Yun, Li Wei, Zhang Wei, Zhu Lian
Department of Cosmetology, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Department of Hematology, Shanghai Putuo District Central Hospital, Shanghai, China.
J Cosmet Dermatol. 2025 Jul;24(7):e70267. doi: 10.1111/jocd.70267.
The growing incidence of adiposity has driven the innovation of potent non-invasive body contouring methodologies. Of these, low-intensity focused ultrasound (LIFU) therapy is recognized for its precision in targeting and destroying stubborn adipose tissue. This study aims to assess the treatment effectiveness and safety of utilizing LIFU in conjunction with radiofrequency for female abdominal contouring.
A prospective clinical trial was performed with a cohort of 20 women, aged 28-42 years, who had a body mass index ranging from 20.40 to 26.82 kg/m and exhibited abdominal skin laxity. We used LIFU and radiofrequency treatments, administered in six sessions over 6 weeks. Efficacy was assessed by measurements of abdominal circumferences using tape, subcutaneous adipose tissue thickness by ultrasound and computed tomography, dermal thickness using ultrasound, and abdominal appearance by standardized photography. The safety was evaluated using pain intensity assessment, nine hematological markers, and adverse events in abdominal appearance.
The treatment led to statistically significant reductions in supraumbilical, periumbilical, and subumbilical abdominal circumferences by 2.08 ± 3.29 cm (2.51%), 2.30 ± 3.23 cm (2.59%), and 3.03 ± 3.39 cm (3.29%), respectively. Similarly, significant decreases were observed in subcutaneous adipose tissue thickness at these sites by 6.46 ± 6.33 mm (27.37%), 6.03 ± 5.95 mm (23.28%), and 8.54 ± 6.94 mm (35.43%). On the other hand, dermal thickness demonstrated a mild increase of 9.17%, and none of the subjects experienced severe pain during the treatment sessions. Hematologic markers remained stable, and no adverse events were reported throughout the treatment period.
This investigation established that implementing low-intensity focused ultrasound alongside radiofrequency resulted in a secure and effective approach for abdominal contouring, contributing a novel strategy to medical practice.
肥胖发生率的不断上升推动了高效非侵入性身体塑形方法的创新。其中，低强度聚焦超声（LIFU）疗法因其在靶向和破坏顽固脂肪组织方面的精准性而受到认可。本研究旨在评估联合使用LIFU和射频进行女性腹部塑形的治疗效果和安全性。
对20名年龄在28 - 42岁、体重指数在20.40至26.82kg/m且有腹部皮肤松弛的女性进行了一项前瞻性临床试验。我们采用LIFU和射频治疗，在6周内分6次进行。通过用卷尺测量腹围、用超声和计算机断层扫描测量皮下脂肪组织厚度、用超声测量真皮厚度以及通过标准化摄影评估腹部外观来评估疗效。通过疼痛强度评估、九项血液学指标以及腹部外观的不良事件来评估安全性。
治疗导致脐上、脐周和脐下腹部周长分别在统计学上显著减少2.08±3.29厘米（2.51%）、2.30±3.23厘米（2.59%）和3.03±3.39厘米（3.29%）。同样，这些部位的皮下脂肪组织厚度也显著减少，分别为6.46±6.33毫米（27.37%）、6.03±5.95毫米（23.28%）和8.54±6.94毫米（35.43%）。另一方面，真皮厚度轻微增加了9.17%，并且在治疗过程中没有受试者经历严重疼痛。血液学指标保持稳定，在整个治疗期间未报告不良事件。
本研究证实，联合使用低强度聚焦超声和射频为腹部塑形提供了一种安全有效的方法，为医学实践贡献了一种新策略。
