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卡里尼丝虫(Litomosoides carinii):沙鼠(Meriones unguiculatus)体内蠕虫生长及激发感染迁移的延缓

Litomosoides carinii: retardation of worm growth and of migration of challenge infections in jirds (Meriones unguiculatus).

作者信息

Weiner D J, Leeds B Y

出版信息

J Helminthol. 1985 Sep;59(3):191-4. doi: 10.1017/s0022149x00007938.

Abstract

Inbred jirds (Meriones unguiculatus) were divided into three groups; each animal in two of the groups was infected with 30 infective larvae (L3) of Litomosoides carinii. When these infections were patent, the jirds of one of the two infected groups plus those of the third group were injected with 30 L3 L. carinii each. All animals were killed either on day 14 or 24 after the second infection for the recovery, enumeration and measurement of all worms and developing larvae. Challenge larvae were stunted (smaller) and fewer than control larvae. Additionally, fewer challenge larva were recovered on day 14 than on day 24, indicating that migration to the pleural cavity was retarded.

摘要

近交系沙鼠(长爪沙鼠)被分为三组;两组中的每只动物都感染了30条卡氏住丝虫感染性幼虫(L3)。当这些感染出现虫血症时,两个感染组中的一组沙鼠以及第三组沙鼠每只都再注射30条卡氏住丝虫L3。在第二次感染后的第14天或第24天,所有动物均被处死,以回收、计数和测量所有蠕虫及发育中的幼虫。攻击感染的幼虫发育不良(较小)且数量少于对照幼虫。此外,在第14天回收的攻击感染幼虫比第24天少,这表明向胸腔的迁移受到了阻碍。

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