Fitsum Solomon, Sbhatu Desta Berhe, Gebreyohannes Gebreselema
Department of Biological and Chemical Engineering Mekelle Institute of Technology, Mekelle University Mekelle Ethiopia.
Food Sci Nutr. 2025 Jul 15;13(7):e70611. doi: 10.1002/fsn3.70611. eCollection 2025 Jul.
Mushrooms have been valued for their unique flavor and medicinal properties since ancient times. As a nutrient-dense superfood, they provide essential nutrients, including dietary fiber, high-quality protein, and key vitamins (especially D and B), along with minerals. They are naturally low in fat, sugar, and calories, and cholesterol, making them a beneficial addition to a balanced diet. Increasingly, mushrooms are incorporated into functional foods, cosmetics, and even used as meat substitutes, enhancing nutritional value and offering significant health benefits. They contain a variety of bioactive compounds-such as terpenoids, flavonoids, tannins, alkaloids, polyphenols, and polysaccharides-which contribute to their therapeutic properties. These include antioxidant, anticancer, antimicrobial, immunomodulatory, anti-inflammatory, anti-tyrosinase, immune-boosting, and antihyperglycemic effects, all of which support human health and medical applications. Additionally, mushrooms promote heart health, help reduce cholesterol, and assist in managing chronic conditions like hypertension, obesity, and diabetes. Ongoing research continues to uncover new bioactive compounds that may be effective in treating neurological and cardiovascular diseases. With advancements in science and technology, mushrooms are becoming increasingly valuable in medicine, pharmaceuticals, food production, cosmetics, and environmental bioremediation, creating potential opportunities across various industries. This review aims to explore the nutritional value and bioactive compounds of mushrooms, along with their health benefits, therapeutic properties, and applications in functional foods, cosmetics, and pharmaceuticals. It highlights their potential as sustainable medicinal resources and a rich source of novel bioactive compounds for managing chronic diseases and other health conditions.
自古以来,蘑菇就因其独特的风味和药用价值而备受重视。作为一种营养丰富的超级食物,它们提供了包括膳食纤维、优质蛋白质、关键维生素(尤其是维生素D和B族维生素)以及矿物质在内的必需营养素。它们天然低脂、低糖、低热量且不含胆固醇,是均衡饮食中有益的添加物。越来越多的蘑菇被用于功能性食品、化妆品中,甚至被用作肉类替代品,提高了营养价值并带来显著的健康益处。它们含有多种生物活性化合物,如萜类化合物、黄酮类化合物、单宁、生物碱、多酚和多糖,这些化合物赋予了它们治疗功效。这些功效包括抗氧化、抗癌、抗菌、免疫调节、抗炎、抗酪氨酸酶、增强免疫力和降血糖作用,所有这些都对人类健康和医学应用有支持作用。此外,蘑菇有助于心脏健康,有助于降低胆固醇,并有助于管理高血压、肥胖症和糖尿病等慢性疾病。正在进行的研究不断发现可能对治疗神经和心血管疾病有效的新生物活性化合物。随着科学技术的进步,蘑菇在医学、制药、食品生产、化妆品和环境生物修复等领域的价值越来越高,为各个行业创造了潜在机会。本综述旨在探讨蘑菇的营养价值、生物活性化合物,以及它们的健康益处、治疗特性,以及在功能性食品、化妆品和制药中的应用。它强调了蘑菇作为可持续药用资源的潜力,以及作为管理慢性疾病和其他健康状况的新型生物活性化合物的丰富来源。