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催化剂:系统化学将反应与分子功能联系起来。

Catalyst: Systems chemistry links reactions to molecular function.

作者信息

Huang Haiyan, McGrath Andrew, Audu Christopher O, Cernak Tim

机构信息

Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA.

出版信息

Chem. 2024 Aug 8;10(8):2333-2336. doi: 10.1016/j.chempr.2024.06.009. Epub 2024 Jul 30.

Abstract

Andrew McGrath completed his PhD studies at the University of Michigan with Tim Cernak, studying amine-acid coupling reactions and their application in medicinal chemistry. Andrew was an undergraduate of the University of Colorado at Colorado Springs and is currently a postdoctoral researcher at Merck & Co., Inc. in Rahway, NJ. Haiyan Huang is currently a postdoctoral fellow in the Cernak Lab at the University of Michigan, where she studies amine-acid coupling reactions. She earned her BSc from Sun Yat-sen University and her PhD studying total synthesis at McGill University under the supervision of Prof. Lumb. Christopher O. Audu is currently a chief resident in vascular surgery at the University of Michigan. He studied at Purdue (BSc) and Dartmouth (MD and PhD) and performed postdoctoral research with Drs. Cernak and Gallagher at the University of Michigan. He will begin an assistant professorship of vascular surgery and chemical research at the University of Utah in the fall of 2024. Tim Cernak is an associate professor of medicinal chemistry at the University of Michigan, exploring the role of data science in chemistry and medicine in biodiversity conservation. Prior to working at the University of Michigan, he worked at Merck & Co., Inc. He is a co-founder of Iambic Therapeutics.

摘要

安德鲁·麦格拉思在密歇根大学与蒂姆·切尔纳克一起完成了他的博士学业,研究胺酸偶联反应及其在药物化学中的应用。安德鲁曾是科罗拉多大学科罗拉多斯普林斯分校的本科生,目前是新泽西州拉威市默克公司的博士后研究员。黄海燕目前是密歇根大学切尔纳克实验室的博士后研究员,她在那里研究胺酸偶联反应。她在中山大学获得理学学士学位,并在伦布教授的指导下于麦吉尔大学攻读全合成博士学位。克里斯托弗·O·奥杜目前是密歇根大学血管外科的总住院医师。他曾在普渡大学(理学学士)和达特茅斯学院(医学博士和哲学博士)学习,并在密歇根大学与切尔纳克博士和加拉格尔博士一起进行博士后研究。他将于2024年秋季开始在犹他大学担任血管外科和化学研究助理教授。蒂姆·切尔纳克是密歇根大学药物化学副教授,探索数据科学在化学和医学中对生物多样性保护的作用。在密歇根大学工作之前,他曾在默克公司工作。他是Iambic Therapeutics公司的联合创始人。

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本文引用的文献

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