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针对精神病的个体认知行为疗法中治疗形式及治疗师培训相关性的探索性研究。

An exploratory study of the relevance of therapy format and therapist' training in individual cognitive behavioral therapy for psychosis.

作者信息

Gjerdalen Oda Skancke, Zucknick Manuela, Westlie Ingvild Tvedt, Bull Helen, Evensen Stig, Falkum Erik, Grande Marit, Hagen Roger, Romm Kristin Lie, Jensen Lene Hunnicke, Ringen Petter Andreas, Schjøtt-Pedersen Olivia, Sönmez Nasrettin, Ueland Torill, Østefjells Tiril, Røssberg Jan Ivar, Lystad June Ullevoldsæter

机构信息

Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.

Oslo Centre for Biostatistics and Epidemiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

出版信息

Front Psychiatry. 2025 Jul 2;16:1527549. doi: 10.3389/fpsyt.2025.1527549. eCollection 2025.

Abstract

INTRODUCTION

Cognitive Behavioral Therapy for psychosis (CBTp) is an evidence-based intervention that can be delivered in various formats, including as part of vocational rehabilitation. However, due to scarcity of resources, CBTp is currently accessible to only a minority of individuals with psychosis. This secondary analysis aims to explore potential differences in clinical outcomes between distinct CBTp formats and to examine whether therapist training influences treatment effect. Exploring these aspects is of importance, as they may influence the scalability and accessibility of CBTp in routine care.

MATERIAL AND METHODS

Data in this study is sourced from two independent projects; and , comprising a total of 200 participants with broad schizophrenia-spectrum disorders. The current study compares CBTp delivered as either symptom-focused individual therapy (KATOslo) or as an add-on to a vocational rehabilitation (VR) program (JUMP), with two reference groups; VR combined with cognitive remediation (JUMP) and treatment as usual (KATOslo). Using a series of mixed effects models for repeated measurements, we examined differences between the groups in terms of general functioning and psychiatric symptom severity. Emphasis was placed on potential differences between the two groups receiving CBTp, considering both average differences across assessment points and trajectories over time.

RESULTS

In line with expectations, all groups demonstrated overall improvements in functioning and symptom levels. After adjusting for relevant confounders, no statistically significant differences were found between the two groups receiving CBTp following treatment initiation.

CONCLUSIONS

These findings suggest that CBTp may be effective across different delivery formats and levels of therapist training in terms of similar, positive clinical outcomes for this patient group. This has potential implications for service design and broader implementation of CBTp in real-world settings.

摘要

引言

精神病认知行为疗法(CBTp)是一种循证干预措施,可通过多种形式提供,包括作为职业康复的一部分。然而,由于资源稀缺,目前只有少数精神病患者能够接受CBTp治疗。这项二次分析旨在探讨不同CBTp形式在临床结果上的潜在差异,并检验治疗师培训是否会影响治疗效果。探索这些方面很重要,因为它们可能会影响CBTp在常规护理中的可扩展性和可及性。

材料与方法

本研究的数据来自两个独立项目;[项目一]和[项目二],共有200名患有广泛精神分裂症谱系障碍的参与者。本研究将以症状为重点的个体治疗(KATOslo)形式或作为职业康复(VR)计划附加内容(JUMP)提供的CBTp与两个参照组进行比较;VR与认知矫正相结合(JUMP)以及常规治疗(KATOslo)。我们使用一系列重复测量的混合效应模型,检查了各组在总体功能和精神症状严重程度方面的差异。重点关注接受CBTp的两组之间的潜在差异,同时考虑评估点之间的平均差异和随时间的变化轨迹。

结果

与预期一致,所有组在功能和症状水平上均有总体改善。在对相关混杂因素进行调整后,开始治疗后接受CBTp的两组之间未发现统计学上的显著差异。

结论

这些发现表明,就该患者群体相似的积极临床结果而言,CBTp可能在不同的提供形式和治疗师培训水平上均有效。这对服务设计以及CBTp在现实环境中的更广泛实施具有潜在意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/12263635/7da7387f5e44/fpsyt-16-1527549-g001.jpg

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