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A型肉毒毒素注射后联合体外冲击波疗法对脑卒中后踝关节跖屈肌痉挛的疗效评估

Evaluation of the efficacy of extracorporeal shock wave therapy following botulinum toxin type a injection on post-stroke ankle plantar flexor spasticity.

作者信息

Talay Çalış Havva, Cansın Fevzi, Koçer Elif, Ülkü Demir Fatma Gül

机构信息

Kayseri Faculty of Medicine, Kayseri City Hospital, Department of Physical Medicine and Rehabilitation, University of Health Sciences, Kayseri, Türkiye.

Kahramanmaraş Necip Fazıl City Hospital, Department of Physical Medicine and Rehabilitation, Kahramanmaraş, Türkiye.

出版信息

Top Stroke Rehabil. 2025 Jul 17:1-9. doi: 10.1080/10749357.2025.2532424.

Abstract

BACKGROUND AND PURPOSE

This study aimed to compare the efficacy of Botulinum Toxin Type A (BoNT-A) injection and BoNT-A injection in combination with ESWT for post-stroke lower extremity ankle plantar flexor spasticity in this prospective, randomized cohort study.

METHODS

Patients with post-stroke ankle plantar flexor spasticity of 1+ or more on the Modified Ashworth Scale (MAS) were randomized into two groups. Group 1 (n:20): BoNT-A was injected into the gastrocnemius muscle, and conventional physical therapy exercises were performed. Group 2 (n:20): ESWT was applied to the gastrocnemius muscle in addition to the treatments in group 1. MAS, Brunnstrom Motor Recovery Stage (BMRS), ankle range of motion (ROM) measurement, clonus score (CS), Barthel Index (BI), Heckmatt measurements with ultrasonography, and visual analog scale (VAS) evaluations were performed on the patients.

RESULTS

No statistically significant differences were observed between the groups in any of the measured parameters at baseline or at any other time ( > 0.05). In both groups, there was a statistically significant improvement in all scores, except for the Heckmatt scores, after treatment compared to before treatment ( < 0.05).

CONCLUSION

ESWT treatment added to BoNT-A was not statistically significantly superior to BoNT-A in terms of MAS, BME, ROM, BI, Heckmatt grade, VAS, and CS. Our study did not observe the additional antispastic contribution of ESWT on spasticity.

摘要

背景与目的

在这项前瞻性随机队列研究中,本研究旨在比较A型肉毒毒素(BoNT-A)注射以及BoNT-A注射联合体外冲击波疗法(ESWT)治疗中风后下肢踝跖屈肌痉挛的疗效。

方法

改良Ashworth量表(MAS)评分为1+或更高的中风后踝跖屈肌痉挛患者被随机分为两组。第1组(n = 20):将BoNT-A注射到腓肠肌,并进行常规物理治疗锻炼。第2组(n = 20):除第1组的治疗外,还对腓肠肌进行ESWT治疗。对患者进行MAS、Brunnstrom运动恢复阶段(BMRS)、踝关节活动范围(ROM)测量、阵挛评分(CS)、Barthel指数(BI)、超声Heckmatt测量以及视觉模拟量表(VAS)评估。

结果

在基线或任何其他时间,两组在任何测量参数上均未观察到统计学上的显著差异(P > 0.05)。与治疗前相比,两组治疗后除Heckmatt评分外的所有评分均有统计学上的显著改善(P < 0.05)。

结论

在MAS、BME、ROM、BI、Heckmatt分级、VAS和CS方面,BoNT-A联合ESWT治疗在统计学上并不显著优于BoNT-A治疗。我们的研究未观察到ESWT对痉挛的额外抗痉挛作用。

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