• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

亲吻作为唾液pH值降低的保护因素:一项随机临床试验方案

Kissing as a Protective Factor Against Decreased Salivary pH: Protocol for a Randomized Clinical Trial.

作者信息

Armijos Briones Marcelo, Aguila Gaibor Mariuxi, Bermúdez Velásquez Andrea

机构信息

Dental School, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.

出版信息

JMIR Res Protoc. 2025 Jul 17;14:e65253. doi: 10.2196/65253.

DOI:10.2196/65253
PMID:40674724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12314465/
Abstract

BACKGROUND

Kissing is a common social behavior that may influence physiological responses and impact oral health. Prior research has shown that affectionate behaviors like kissing can reduce stress and improve relationship satisfaction. However, the effects of kissing on salivary pH, particularly after consuming sugary or fermented beverages, have not been thoroughly investigated.

OBJECTIVE

This study aims to determine whether kissing accelerates salivary pH recovery following the consumption of sugary or fermented beverages.

METHODS

A randomized controlled trial will be conducted with 60 couples aged 18-30 years. Participants will be divided into 3 groups: a control group (no kissing), an experimental group where one partner consumes a beverage, and another experimental group where both partners consume a beverage. The study will measure salivary pH at baseline, after beverage consumption, and following a 40-second kiss or control period, with measurements taken every 5 minutes until the pH returns to neutral levels. The data will be analyzed using SPSS software (IBM Corporation). ANOVA will be used to compare salivary pH recovery between groups, and if assumptions of normality or sphericity are not met, alternative models such as generalized linear models or nonparametric tests will be considered.

RESULTS

The study is ongoing, with participant recruitment already initiated and preliminary data collection in progress. The study was funded by the Catholic University of Santiago de Guayaquil from June 2024 to June 2025. Ethics approval was obtained in June 2023. The results are expected to be published in the last quarter of 2025.

CONCLUSIONS

This study will provide insights into the relationship between kissing, salivary pH, and oral health, potentially offering new strategies for the prevention of dental caries. The results may challenge existing assumptions about the role of kissing in oral health.

TRIAL REGISTRATION

ClinicalTrials.gov NCT06501729; https://clinicaltrials.gov/study/NCT06501729.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/65253.

摘要

背景

亲吻是一种常见的社交行为,可能会影响生理反应并对口腔健康产生影响。先前的研究表明,像亲吻这样的亲昵行为可以减轻压力并提高关系满意度。然而,亲吻对唾液pH值的影响,尤其是在饮用含糖或发酵饮料后,尚未得到充分研究。

目的

本研究旨在确定亲吻是否能加速饮用含糖或发酵饮料后唾液pH值的恢复。

方法

将对60对年龄在18至30岁之间的夫妇进行一项随机对照试验。参与者将被分为3组:对照组(不亲吻)、一个伴侣饮用饮料的实验组和两个伴侣都饮用饮料的另一个实验组。该研究将在基线、饮用饮料后以及40秒亲吻或对照期后测量唾液pH值,每5分钟测量一次,直到pH值恢复到中性水平。数据将使用SPSS软件(IBM公司)进行分析。方差分析将用于比较各组之间唾液pH值的恢复情况,如果不满足正态性或球形性假设,将考虑替代模型,如广义线性模型或非参数检验。

结果

该研究正在进行中,已经开始招募参与者并正在进行初步数据收集。该研究由瓜亚基尔天主教大学于2024年6月至2025年6月资助。2023年6月获得伦理批准。预计结果将于2025年最后一个季度发表。

结论

本研究将深入了解亲吻、唾液pH值和口腔健康之间的关系,可能为预防龋齿提供新策略。研究结果可能会挑战关于亲吻在口腔健康中作用的现有假设。

试验注册

ClinicalTrials.gov NCT06501729;https://clinicaltrials.gov/study/NCT06501729。

国际注册报告标识符(IRRID):DERR1-10.2196/65253。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c9f/12314465/1bf16db66797/resprot_v14i1e65253_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c9f/12314465/1bf16db66797/resprot_v14i1e65253_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c9f/12314465/1bf16db66797/resprot_v14i1e65253_fig1.jpg

相似文献

1
Kissing as a Protective Factor Against Decreased Salivary pH: Protocol for a Randomized Clinical Trial.亲吻作为唾液pH值降低的保护因素:一项随机临床试验方案
JMIR Res Protoc. 2025 Jul 17;14:e65253. doi: 10.2196/65253.
2
Sexual Harassment and Prevention Training性骚扰与预防培训
3
The Black Book of Psychotropic Dosing and Monitoring.《精神药物剂量与监测黑皮书》
Psychopharmacol Bull. 2024 Jul 8;54(3):8-59.
4
Antioxidants for male subfertility.用于男性生育力低下的抗氧化剂。
Cochrane Database Syst Rev. 2014(12):CD007411. doi: 10.1002/14651858.CD007411.pub3. Epub 2014 Dec 15.
5
Atraumatic restorative treatment versus conventional restorative treatment for managing dental caries.非创伤性修复治疗与传统修复治疗在龋病管理中的比较
Cochrane Database Syst Rev. 2017 Dec 28;12(12):CD008072. doi: 10.1002/14651858.CD008072.pub2.
6
Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation.静脉注射硫酸镁和索他洛尔预防冠状动脉搭桥术后房颤:系统评价与经济学评估
Health Technol Assess. 2008 Jun;12(28):iii-iv, ix-95. doi: 10.3310/hta12280.
7
Topical antiseptics for chronic suppurative otitis media.用于慢性化脓性中耳炎的局部用抗菌剂。
Cochrane Database Syst Rev. 2025 Jun 9;6(6):CD013055. doi: 10.1002/14651858.CD013055.pub3.
8
Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis.运动神经元病/肌萎缩侧索硬化症患者流涎(唾液过多)的治疗。
Cochrane Database Syst Rev. 2022 May 20;5(5):CD006981. doi: 10.1002/14651858.CD006981.pub3.
9
Psychological interventions for adults who have sexually offended or are at risk of offending.针对有性犯罪行为或有性犯罪风险的成年人的心理干预措施。
Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD007507. doi: 10.1002/14651858.CD007507.pub2.
10
Behavioral interventions to reduce risk for sexual transmission of HIV among men who have sex with men.降低男男性行为者中艾滋病毒性传播风险的行为干预措施。
Cochrane Database Syst Rev. 2008 Jul 16(3):CD001230. doi: 10.1002/14651858.CD001230.pub2.

本文引用的文献

1
The Use of Patient-Oriented Mobile Phone Apps in Oral Health: Scoping Review.患者导向型手机应用在口腔健康中的应用:范围综述。
JMIR Mhealth Uhealth. 2023 Sep 6;11:e46143. doi: 10.2196/46143.
2
Fermented Pineapple Juice Consumption Limits Metabolic Disorders Associated to Sugary Drinks on High-Fat Diet-Fed Mice.发酵菠萝汁可限制高脂肪饮食喂养的小鼠因含糖饮料导致的代谢紊乱。
Mol Nutr Food Res. 2023 Jun;67(11):e2200670. doi: 10.1002/mnfr.202200670. Epub 2023 May 19.
3
Apps for Promoting Children's Oral Health: Systematic Search in App Stores and Quality Evaluation.
促进儿童口腔健康的应用程序:在应用商店中的系统搜索与质量评估
JMIR Pediatr Parent. 2022 Jun 6;5(2):e28238. doi: 10.2196/28238.
4
Romantic partner embraces reduce cortisol release after acute stress induction in women but not in men.浪漫伴侣的拥抱可减少女性在急性应激诱导后的皮质醇释放,但对男性则不然。
PLoS One. 2022 May 18;17(5):e0266887. doi: 10.1371/journal.pone.0266887. eCollection 2022.
5
Comparison of Salivary pH Changes after Consumption of Two Sweetened Malaysian Local Drinks among Individuals with Low Caries Experience: A Pilot Study.低龋经验个体饮用两种马来西亚甜味本地饮品后唾液pH值变化的比较:一项初步研究
Malays J Med Sci. 2018 Jul;25(4):100-111. doi: 10.21315/mjms2018.25.4.10. Epub 2018 Aug 30.
6
The effects of family, dentition, and dental caries on the salivary microbiome.家庭、牙列和龋齿对唾液微生物群的影响。
Ann Epidemiol. 2016 May;26(5):348-54. doi: 10.1016/j.annepidem.2016.03.006. Epub 2016 Apr 9.
7
Effect of Various Sugary Beverages on Salivary pH, Flow Rate, and Oral Clearance Rate amongst Adults.不同含糖饮料对成年人唾液pH值、流速及口腔清除率的影响
Scientifica (Cairo). 2016;2016:5027283. doi: 10.1155/2016/5027283. Epub 2016 Mar 8.
8
CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials.CONSORT 2010解释与详述:平行组随机试验报告的更新指南
BMJ. 2010 Mar 23;340:c869. doi: 10.1136/bmj.c869.
9
Short-term regulation of acid-base homeostasis of body fluids.体液酸碱平衡的短期调节
Br J Nurs. 2007;16(16):1016-21. doi: 10.12968/bjon.2007.16.16.27082.
10
Dental caries.龋齿
Lancet. 2007 Jan 6;369(9555):51-9. doi: 10.1016/S0140-6736(07)60031-2.