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三种不同非手术牙周刮治方法治疗牙周炎的随机对照临床研究

Management of periodontitis by three different approaches to non-surgical periodontal debridement- a randomized comparative clinical study.

作者信息

Chathurika Padmakumari Kodikara Mudiyanselage, Gunasekara Uthpala Muhandiramge, Pallegama Ranjith, Tilakaratne Aruni

机构信息

Postgraduate Institute of Medicine, University of Colombo, Colombo, Sri Lanka.

Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.

出版信息

BMC Oral Health. 2025 Jul 17;25(1):1185. doi: 10.1186/s12903-025-06595-x.

Abstract

BACKGROUND

Non-surgical periodontal therapy (NSPT) is the cornerstone of periodontitis management. This comparative clinical study evaluates the effectiveness of three different non-surgical treatment approaches in three treatment groups, namely, Quadrant-wise Scaling and Root Surface Debridement (Q-Sc + RSD), Full-mouth Disinfection (FMDis), and Full-mouth Debridement (FMDeb).

METHODS

A total of 45 patients with generalised stage II and III periodontitis were randomly assigned to one of the three treatment groups. Plaque scores (PS), bleeding scores (BS) and probing pocket depths (PD) were recorded at baseline and post-NSPT. Data were analyzed to compare the changes in PS, BS, and PD distribution at baseline and post-NSPT in all three groups.

RESULTS

All three treatment approaches resulted in statistically significant reductions in PS, BS, and PD distribution compared to baseline. However, FMDeb and FMDis protocols demonstrated greater reductions in BS and PD distribution compared to the Q-Sc + RSD protocol. Remarkably low BS were observed in all three study groups at the post-treatment evaluation, with statistically significant differences compared to their respective pre-treatment BS.

CONCLUSIONS

All three treatment approaches were effective in reducing PS, BS, and PD in patients with periodontitis, while FMDeb and FMDis protocols demonstrated superior effectiveness in terms of reduction of BS and PD, compared to the Q-Sc + RSD protocol. Further research with larger sample sizes and longer follow-up periods may be warranted to confirm these findings and evaluate the long-term clinical outcomes of these different debridement approaches of NSPT.

CLINICAL TRIAL NO

The UK's Clinical Study Registry ISRCTN13350022, 28/05/2025, retrospectively registered.

摘要

背景

非手术牙周治疗(NSPT)是牙周炎治疗的基石。这项比较性临床研究评估了三个治疗组中三种不同非手术治疗方法的有效性,即象限刮治和根面平整(Q-Sc + RSD)、全口消毒(FMDis)和全口清创(FMDeb)。

方法

总共45例广泛性II期和III期牙周炎患者被随机分配到三个治疗组之一。在基线和NSPT治疗后记录菌斑评分(PS)、出血评分(BS)和探诊深度(PD)。分析数据以比较所有三组在基线和NSPT治疗后的PS、BS和PD分布变化。

结果

与基线相比,所有三种治疗方法均导致PS、BS和PD分布在统计学上显著降低。然而,与Q-Sc + RSD方案相比,FMDeb和FMDis方案在BS和PD分布方面的降低幅度更大。在治疗后评估中,所有三个研究组的BS均显著较低,与各自治疗前的BS相比有统计学显著差异。

结论

所有三种治疗方法在降低牙周炎患者的PS、BS和PD方面均有效,而与Q-Sc + RSD方案相比,FMDeb和FMDis方案在降低BS和PD方面显示出更高的有效性。可能需要进行更大样本量和更长随访期的进一步研究以证实这些发现并评估这些不同NSPT清创方法的长期临床结果。

临床试验编号

英国临床研究注册中心ISRCTN13350022,2025年5月28日,回顾性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ab8/12273010/536a0940e7e6/12903_2025_6595_Fig1_HTML.jpg

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