Swierkot Katrin, Nonnenmacher Claudia Ivana, Mutters Reinier, Flores-de-Jacoby Lavin, Mengel Reiner
Department of Periodontology, Philipps University, Marburg, Germany.
J Clin Periodontol. 2009 Mar;36(3):240-9. doi: 10.1111/j.1600-051X.2008.01368.x.
The aim of this study was to test the hypothesis that the one-stage full-mouth disinfection (FMD) provides greater clinical and microbiological improvement compared with full-mouth scaling and root planing (FM-SRP) within 24 h and quadrant scaling and root planing (Q-SRP) in patients with generalized chronic periodontitis.
MATERIAL & METHODS: Twenty-eight patients were randomized into three groups. 25 patients completed the study and were the basis for analysis. The Q-SRP group was scaled quadrant-wise at 1-week intervals. The other groups received a one-stage full-mouth scaling with (FMD) and without (FM-SRP) chlorhexidine. At baseline, after 1, 2, 4 and 8 months clinical parameters were recorded and microbiological analysis was performed.
All three treatment modalities resulted in significant clinical improvement at any time. There were only group differences after 1 and 2 months: in the FM-SRP group was a significantly higher reduction of probing depth and bleeding on probing compared with the other two groups. The bacteria could be reduced in every group although this reduction was only significant for Prevotella intermedia in the FMD group 8 months after treatment.
All three treatment modalities lead to an improvement of the clinical and microbiological parameters, however, without significant group differences after 8 months.
本研究旨在验证以下假设:对于广泛性慢性牙周炎患者,与全口龈上洁治和根面平整术(FM-SRP)以及分象限龈上洁治和根面平整术(Q-SRP)相比,一次性全口消毒(FMD)在24小时内可带来更大的临床和微生物学改善。
28例患者被随机分为三组。25例患者完成了研究并作为分析的基础。Q-SRP组每隔1周按象限进行洁治。其他组分别接受含(FMD)和不含(FM-SRP)氯己定的一次性全口洁治。在基线、1、2、4和8个月时记录临床参数并进行微生物学分析。
所有三种治疗方式在任何时候都带来了显著的临床改善。仅在1个月和2个月后存在组间差异:FM-SRP组与其他两组相比,探诊深度和探诊出血的减少更为显著。每组中的细菌数量均可减少,尽管仅在治疗8个月后FMD组的中间普氏菌数量减少具有显著性。
所有三种治疗方式均可改善临床和微生物学参数,然而,8个月后各组之间无显著差异。