Department of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid, ES.
Cardiology Department, Hospital Universitario Ramon y Cajal, Madrid, ES.
Glob Heart. 2020 Feb 3;15(1):1. doi: 10.5334/gh.400.
In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non-communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of the world's population, the sixth most common human disease.
There is now a significant body of evidence to support independent associations between severe periodontitis and several NCDs, in particular CVD. In 2012 a joint workshop was held between the European Federation of Periodontology (EFP) and the American Academy of Periodontology to review the literature relating periodontitis and systemic diseases, including CVD. In the last five years important new scientific information has emerged providing important emerging evidence to support these associations.
The present review reports the proceedings of the workshop jointly organised by the EFP and the World Heart Federation (WHF), which has updated the existing epidemiological evidence for significant associations between periodontitis and CVD, the mechanistic links and the impact of periodontal therapy on cardiovascular and surrogate outcomes. This review has also focused on the potential risk and complications of periodontal therapy in patients on anti thrombotic therapy and has made recommendations for dentists, physicians and for patients visiting both the dental and medical practices.
在欧洲，心血管疾病（CVD）导致 390 万人死亡（占死亡人数的 45%），缺血性心脏病、中风和高血压（导致心力衰竭）是这些与 CVD 相关死亡的主要原因。牙周炎也是一种高发的慢性非传染性疾病（NCD）。严重的牙周炎影响了全球 11.2%的人口，是第六大常见人类疾病。
现在有大量证据支持严重牙周炎与几种 NCD，特别是 CVD 之间存在独立关联。2012 年，欧洲牙周病学会（EFP）和美国牙周病学会联合举办了一次研讨会，审查了牙周炎与系统性疾病（包括 CVD）相关的文献。在过去的五年中，出现了重要的新科学信息，为这些关联提供了重要的新证据。
本综述报告了 EFP 和世界心脏联合会（WHF）联合组织的研讨会的会议记录，该研讨会更新了牙周炎与 CVD 之间存在显著关联的现有流行病学证据、机制联系以及牙周治疗对心血管和替代终点的影响。本综述还重点关注了抗血栓治疗患者进行牙周治疗的潜在风险和并发症，并为牙医、内科医生以及同时访问牙科和内科的患者提出了建议。
