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冷冻对兔股骨头骨骺生长板组织学及生物力学破坏模式的影响

Effect of freezing on histologic and biomechanical failure patterns in the rabbit capital femoral growth plate.

作者信息

Lee K E, Pelker R R

出版信息

J Orthop Res. 1985;3(4):514-5. doi: 10.1002/jor.1100030415.

DOI:10.1002/jor.1100030415
PMID:4067709
Abstract

Ten pairs of proximal femora were harvested from 8-week-old New Zealand white rabbits. Experimental shear fractures were then created in vitro, and load-displacement curves were recorded. One specimen from each animal was tested within 4 h of death, whereas the contralateral specimen was frozen for 10 to 20 days and thawed prior to testing. Histologic sections of the fractured specimens were studied. No statistically significant differences could be demonstrated between the fresh and the frozen/thawed specimens in either the histologic patterns or the shear load or stress to failure.

摘要

从8周龄的新西兰白兔身上获取了十对近端股骨。然后在体外制造实验性剪切骨折,并记录载荷-位移曲线。每只动物的一个标本在死亡后4小时内进行测试,而对侧标本则冷冻10至20天,在测试前解冻。对骨折标本进行了组织学切片研究。在组织学模式、剪切载荷或破坏应力方面,新鲜标本与冷冻/解冻标本之间均未显示出统计学上的显著差异。

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