Rudicel S, Pelker R R, Lee K E, Ogden J A, Panjabi M M
J Pediatr Orthop. 1985 Jan-Feb;5(1):27-31. doi: 10.1097/01241398-198501000-00006.
Shear fractures were created through the capital femoral physes of rabbits 2, 4, 6, 10, and 14 weeks of age. Biomechanically, the load to complete failure (i.e., fracture) increased with maturation. The load to failure increased with increasing area of the capital femoral physis. The shear stress increased with age and then began to plateau at 10 weeks of age. Histologically, the zone of failure involved the columnar zone in the specimens from rabbits 2-6 weeks old, progressed to the junction of the columnar and hypertrophic zones in the specimens from 10-week-old rabbits, and occurred within the zone of hypertrophy in the specimens from 14-week-old rabbits. Fractures progressed from a type I physeal fracture in the specimens from rabbits 4-6 weeks old to a type II physeal/metaphyseal fracture in the specimens from older animals, with the metaphyseal fragment increasing in size with increasing chondroosseous maturation of the specimen.
在2周、4周、6周、10周和14周龄的兔股骨近端骺板处制造剪切骨折。从生物力学角度来看，导致完全失效（即骨折）的负荷随成熟度增加而增加。导致失效的负荷随股骨近端骺板面积的增加而增加。剪切应力随年龄增长而增加，然后在10周龄时开始趋于平稳。组织学上，失效区域在2至6周龄兔的标本中涉及柱状区，在10周龄兔的标本中进展到柱状区和肥大区的交界处，在14周龄兔的标本中出现在肥大区内。骨折从4至6周龄兔的标本中的I型骺板骨折发展为年龄较大动物的标本中的II型骺板/干骺端骨折，干骺端碎片的大小随标本软骨骨成熟度的增加而增大。
