Jin J, Xu K, Pan X H, Ma Q Q, Wang L, Chen J F
Hangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou 310021, China.
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2025 Jul 10;46(7):1249-1254. doi: 10.3760/cma.j.cn112338-20250113-00031.
To analyze the utilization of pre-exposure prophylaxis (PrEP) service against HIV and related factors in young men who have sex with men (MSM) in Hangzhou. A cross-sectional study design was used in this questionnaire survey in young MSM recurited through local MSM social organization in Hangzhou from September 2022 to March 2023. The estimated sample size was 242. The information about the social-demographic characteristics, behavioral characteristics, utilization of the post exposure prophylaxis (PEP) service, awareness and utilization of PrEP service of the young MSM were collected. Logistic regression model was used to analyze the related factors of the PrEP utilization. A total of 273 young MSM aged 16- 24 years were surveyed in the study. A total for 20.1% (55/273) of them had used PrEP service. Multivariate logistic regression analysis showed that the factors related to PrEP service utilization included age 16-20 years (a=3.03, 95%:1.12-8.20), education level of senior high school or below (a=2.83, 95%:1.09-7.35), full-time/part-time work (a=3.25, 95% 1.26-8.38), homosexual activity in the past 6 months (a=6.71, 95%:1.84-24.55), inquiring medical staff about PrEP (a=4.71, 95%:1.99-11.13) and PEP service use (a=6.09, 95%:2.69-13.81). The utilization rate of PrEP service was low in young MSM in Hangzhou. It is necessary to strengthen the health education about PrEP and improve the undertanding of PrEP and service capability of medical staff to promote the utilization of PrEP service in young MSM.
分析杭州市男男性行为者(MSM)中艾滋病病毒暴露前预防(PrEP)服务的利用情况及相关因素。本问卷调查采用横断面研究设计,于2022年9月至2023年3月通过杭州市当地男男性行为者社会组织招募年轻男男性行为者。估计样本量为242。收集了年轻男男性行为者的社会人口学特征、行为特征、暴露后预防(PEP)服务利用情况、PrEP服务知晓率和利用率等信息。采用Logistic回归模型分析PrEP利用的相关因素。本研究共调查了273名年龄在16至24岁的年轻男男性行为者。其中共有20.1%(55/273)的人使用过PrEP服务。多因素Logistic回归分析显示,与PrEP服务利用相关的因素包括年龄16至20岁(a=3.03,95%CI:1.12-8.20)、高中及以下文化程度(a=2.83,95%CI:1.09-7.35)、全职/兼职工作(a=3.25,95%CI:1.26-8.38)、过去6个月有同性恋行为(a=6.71,95%CI:1.84-24.55)、向医务人员询问过PrEP(a=4.71,95%CI:1.99-11.13)和使用过PEP服务(a=6.09,95%CI:2.69-13.81)。杭州市年轻男男性行为者中PrEP服务利用率较低。有必要加强PrEP健康教育,提高对PrEP的认识以及医务人员的服务能力,以促进年轻男男性行为者对PrEP服务的利用。